Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014231481> ?p ?o ?g. }
- W2014231481 endingPage "e76133" @default.
- W2014231481 startingPage "e76133" @default.
- W2014231481 abstract "Human insulin-like growth factor 1 Ec (IGF-1Ec), also called mechano growth factor (MGF), is a splice variant of insulin-like growth factor 1 (IGF-1), which has been shown in vitro as well as in vivo to induce growth and hypertrophy in mechanically stimulated or damaged muscle. Growth, hypertrophy and responses to mechanical stimulation are important reactions of cartilaginous tissues, especially those in growth plates. Therefore, we wanted to ascertain if MGF is expressed in growth plate cartilage and if it influences proliferation of chondrocytes, as it does in musculoskeletal tissues. MGF expression was analyzed in growth plate and control tissue samples from piglets aged 3 to 6 weeks. Furthermore, growth plate chondrocyte cell culture was used to evaluate the effects of the MGF peptide on proliferation. We showed that MGF is expressed in considerable amounts in the tissues evaluated. We found the MGF peptide to be primarily located in the cytoplasm, and in some instances, it was also found in the nucleus of the cells. Addition of MGF peptides was not associated with growth plate chondrocyte proliferation." @default.
- W2014231481 created "2016-06-24" @default.
- W2014231481 creator A5010747391 @default.
- W2014231481 creator A5021204520 @default.
- W2014231481 creator A5028622340 @default.
- W2014231481 creator A5030159697 @default.
- W2014231481 creator A5039743039 @default.
- W2014231481 creator A5051877218 @default.
- W2014231481 creator A5054717203 @default.
- W2014231481 creator A5061262968 @default.
- W2014231481 creator A5081934588 @default.
- W2014231481 date "2013-10-11" @default.
- W2014231481 modified "2023-10-17" @default.
- W2014231481 title "Insulin-Like Growth Factor I (IGF-1) Ec/Mechano Growth Factor – A Splice Variant of IGF-1 within the Growth Plate" @default.
- W2014231481 cites W110435328 @default.
- W2014231481 cites W1488424161 @default.
- W2014231481 cites W1492223553 @default.
- W2014231481 cites W1493968401 @default.
- W2014231481 cites W1530473805 @default.
- W2014231481 cites W1545380907 @default.
- W2014231481 cites W1970888117 @default.
- W2014231481 cites W1972527462 @default.
- W2014231481 cites W1979125524 @default.
- W2014231481 cites W1981147953 @default.
- W2014231481 cites W1982679394 @default.
- W2014231481 cites W1983652310 @default.
- W2014231481 cites W1988137138 @default.
- W2014231481 cites W1988904306 @default.
- W2014231481 cites W1992703713 @default.
- W2014231481 cites W1997620569 @default.
- W2014231481 cites W2009069799 @default.
- W2014231481 cites W2013988242 @default.
- W2014231481 cites W2014390932 @default.
- W2014231481 cites W2016181549 @default.
- W2014231481 cites W2022200688 @default.
- W2014231481 cites W2023220045 @default.
- W2014231481 cites W2024394264 @default.
- W2014231481 cites W2028571508 @default.
- W2014231481 cites W2036100674 @default.
- W2014231481 cites W2036624139 @default.
- W2014231481 cites W2039225176 @default.
- W2014231481 cites W2039492777 @default.
- W2014231481 cites W2041522326 @default.
- W2014231481 cites W2046989794 @default.
- W2014231481 cites W2047493823 @default.
- W2014231481 cites W2048204853 @default.
- W2014231481 cites W2049799057 @default.
- W2014231481 cites W2055424082 @default.
- W2014231481 cites W2058268504 @default.
- W2014231481 cites W2062277304 @default.
- W2014231481 cites W2064388179 @default.
- W2014231481 cites W2075425108 @default.
- W2014231481 cites W2102303758 @default.
- W2014231481 cites W2104808399 @default.
- W2014231481 cites W2108743168 @default.
- W2014231481 cites W2117876502 @default.
- W2014231481 cites W2119607029 @default.
- W2014231481 cites W2120443344 @default.
- W2014231481 cites W2132448574 @default.
- W2014231481 cites W2132716318 @default.
- W2014231481 cites W2147169548 @default.
- W2014231481 cites W2150793811 @default.
- W2014231481 cites W2152085045 @default.
- W2014231481 cites W2155557543 @default.
- W2014231481 cites W2163624468 @default.
- W2014231481 cites W2166146113 @default.
- W2014231481 cites W2187544091 @default.
- W2014231481 cites W2275579348 @default.
- W2014231481 cites W3140002906 @default.
- W2014231481 cites W4250247029 @default.
- W2014231481 doi "https://doi.org/10.1371/journal.pone.0076133" @default.
- W2014231481 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3795771" @default.
- W2014231481 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24146828" @default.
- W2014231481 hasPublicationYear "2013" @default.
- W2014231481 type Work @default.
- W2014231481 sameAs 2014231481 @default.
- W2014231481 citedByCount "19" @default.
- W2014231481 countsByYear W20142314812014 @default.
- W2014231481 countsByYear W20142314812015 @default.
- W2014231481 countsByYear W20142314812016 @default.
- W2014231481 countsByYear W20142314812017 @default.
- W2014231481 countsByYear W20142314812018 @default.
- W2014231481 countsByYear W20142314812019 @default.
- W2014231481 countsByYear W20142314812020 @default.
- W2014231481 countsByYear W20142314812023 @default.
- W2014231481 crossrefType "journal-article" @default.
- W2014231481 hasAuthorship W2014231481A5010747391 @default.
- W2014231481 hasAuthorship W2014231481A5021204520 @default.
- W2014231481 hasAuthorship W2014231481A5028622340 @default.
- W2014231481 hasAuthorship W2014231481A5030159697 @default.
- W2014231481 hasAuthorship W2014231481A5039743039 @default.
- W2014231481 hasAuthorship W2014231481A5051877218 @default.
- W2014231481 hasAuthorship W2014231481A5054717203 @default.
- W2014231481 hasAuthorship W2014231481A5061262968 @default.
- W2014231481 hasAuthorship W2014231481A5081934588 @default.
- W2014231481 hasBestOaLocation W20142314811 @default.
- W2014231481 hasConcept C105702510 @default.
- W2014231481 hasConcept C126322002 @default.