FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014232879> ?p ?o ?g. }

• W2014232879 endingPage "437" @default.
• W2014232879 startingPage "431" @default.
• W2014232879 abstract "Purified leukotriene A4 hydrolase from human leukocytes is shown to exhibit peptidase activity towards the synthetic substrates alanine-4-nitroanilide and leucine-4-nitroanilide. The enzymatic activity is abolished after heat treatment (70 degrees C, 30 min). At 37 degrees C these substrates are hydrolyzed at a rate of 380 and 130 nmol/mg/min, respectively, and there is no enzyme inhibition during catalysis. Apo-leukotriene A4 hydrolase, obtained by removal of the intrinsic zinc atom, exhibits only a low peptidase activity which can be restored by the addition of stoichiometric amounts of zinc. Reconstitution of the apoenzyme with cobalt results in a peptidase activity which exceeds that of enzyme reactivated with zinc. Preincubation of the native enzyme with leukotriene A4 reduces the peptidase activity. Semipurified preparations of bovine intestinal aminopeptidase and porcine kidney aminopeptidase do not hydrolyze leukotriene A4 into leukotriene B4." @default.
• W2014232879 created "2016-06-24" @default.
• W2014232879 creator A5048926689 @default.
• W2014232879 creator A5054559822 @default.
• W2014232879 creator A5071054945 @default.
• W2014232879 creator A5082042696 @default.
• W2014232879 date "1990-11-01" @default.
• W2014232879 modified "2023-10-02" @default.
• W2014232879 title "Leukotriene A4 hydrolase: An epoxide hydrolase with peptidase activity" @default.
• W2014232879 cites W1483781996 @default.
• W2014232879 cites W1489769246 @default.
• W2014232879 cites W1510468445 @default.
• W2014232879 cites W1517445962 @default.
• W2014232879 cites W1571341395 @default.
• W2014232879 cites W1576494830 @default.
• W2014232879 cites W1864533597 @default.
• W2014232879 cites W1948956821 @default.
• W2014232879 cites W1965950297 @default.
• W2014232879 cites W1978911402 @default.
• W2014232879 cites W1987002493 @default.
• W2014232879 cites W2004351423 @default.
• W2014232879 cites W2009304199 @default.
• W2014232879 cites W2021116136 @default.
• W2014232879 cites W2024176341 @default.
• W2014232879 cites W2030281527 @default.
• W2014232879 cites W2041345923 @default.
• W2014232879 cites W2042871417 @default.
• W2014232879 cites W2056675361 @default.
• W2014232879 cites W2059516317 @default.
• W2014232879 cites W2078305865 @default.
• W2014232879 cites W2079139053 @default.
• W2014232879 cites W2084451293 @default.
• W2014232879 cites W2140746963 @default.
• W2014232879 cites W2155014088 @default.
• W2014232879 cites W2159792557 @default.
• W2014232879 cites W4293247451 @default.
• W2014232879 cites W923811058 @default.
• W2014232879 doi "https://doi.org/10.1016/s0006-291x(05)81076-9" @default.
• W2014232879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2256933" @default.
• W2014232879 hasPublicationYear "1990" @default.
• W2014232879 type Work @default.
• W2014232879 sameAs 2014232879 @default.
• W2014232879 citedByCount "132" @default.
• W2014232879 countsByYear W20142328792012 @default.
• W2014232879 countsByYear W20142328792013 @default.
• W2014232879 countsByYear W20142328792014 @default.
• W2014232879 countsByYear W20142328792015 @default.
• W2014232879 countsByYear W20142328792016 @default.
• W2014232879 countsByYear W20142328792017 @default.
• W2014232879 countsByYear W20142328792018 @default.
• W2014232879 countsByYear W20142328792019 @default.
• W2014232879 countsByYear W20142328792022 @default.
• W2014232879 crossrefType "journal-article" @default.
• W2014232879 hasAuthorship W2014232879A5048926689 @default.
• W2014232879 hasAuthorship W2014232879A5054559822 @default.
• W2014232879 hasAuthorship W2014232879A5071054945 @default.
• W2014232879 hasAuthorship W2014232879A5082042696 @default.
• W2014232879 hasConcept C101819947 @default.
• W2014232879 hasConcept C178790620 @default.
• W2014232879 hasConcept C181199279 @default.
• W2014232879 hasConcept C185592680 @default.
• W2014232879 hasConcept C203014093 @default.
• W2014232879 hasConcept C2776042228 @default.
• W2014232879 hasConcept C2776452501 @default.
• W2014232879 hasConcept C2776580952 @default.
• W2014232879 hasConcept C2776685179 @default.
• W2014232879 hasConcept C2776914184 @default.
• W2014232879 hasConcept C2780120296 @default.
• W2014232879 hasConcept C2780985610 @default.
• W2014232879 hasConcept C28212737 @default.
• W2014232879 hasConcept C515207424 @default.
• W2014232879 hasConcept C535196362 @default.
• W2014232879 hasConcept C55493867 @default.
• W2014232879 hasConcept C86803240 @default.
• W2014232879 hasConcept C87644729 @default.
• W2014232879 hasConcept C94412978 @default.
• W2014232879 hasConceptScore W2014232879C101819947 @default.
• W2014232879 hasConceptScore W2014232879C178790620 @default.
• W2014232879 hasConceptScore W2014232879C181199279 @default.
• W2014232879 hasConceptScore W2014232879C185592680 @default.
• W2014232879 hasConceptScore W2014232879C203014093 @default.
• W2014232879 hasConceptScore W2014232879C2776042228 @default.
• W2014232879 hasConceptScore W2014232879C2776452501 @default.
• W2014232879 hasConceptScore W2014232879C2776580952 @default.
• W2014232879 hasConceptScore W2014232879C2776685179 @default.
• W2014232879 hasConceptScore W2014232879C2776914184 @default.
• W2014232879 hasConceptScore W2014232879C2780120296 @default.
• W2014232879 hasConceptScore W2014232879C2780985610 @default.
• W2014232879 hasConceptScore W2014232879C28212737 @default.
• W2014232879 hasConceptScore W2014232879C515207424 @default.
• W2014232879 hasConceptScore W2014232879C535196362 @default.
• W2014232879 hasConceptScore W2014232879C55493867 @default.
• W2014232879 hasConceptScore W2014232879C86803240 @default.
• W2014232879 hasConceptScore W2014232879C87644729 @default.
• W2014232879 hasConceptScore W2014232879C94412978 @default.
• W2014232879 hasIssue "1" @default.
• W2014232879 hasLocation W20142328791 @default.
• W2014232879 hasLocation W20142328792 @default.

• next