FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014238497> ?p ?o ?g. }

• W2014238497 endingPage "54" @default.
• W2014238497 startingPage "49" @default.
• W2014238497 abstract "Chronic myelogenous leukemia (CML) is a malignant myeloproliferative disorder that originates from a pluripotent stem cell expressing the bcr-abl oncogene. It is characterized by an abnormal release of the expanded, malignant stem cell clone from the bone marrow into the circulation. The stromal cell derived factor-1 (SDF-1) gene contains a common polymorphism, termed SDF1-3'A, in an evolutionarily conserved segment of the 3' untranslated region (UTR). In this work the SDF-1 genotypes of 25 patients (9-82 years old) who had been clinically and hematologically diagnosed with CML were compared with those of 60 healthy donors. In addition, the nature of bcr-abl hybrid mRNA and the association between demographic and hematological parameters were analyzed in cells from 12 CML patients (five women and seven men). All patients underwent blood collection during the chronic phase of disease after they received chemotherapy. b3a2 mRNA was detected in samples from eight of the CML patients and b2a2 mRNA was observed in four cases. An association between basophils and hemoglobin parameters was observed in that hemoglobin levels were higher in b2a2-expressing patients, and mean basophil levels were higher in patients expressing b3a2. Four of the CML patients (16%) were homozygous for 3'A allele. Of the patients who showed the presence of bcr-abl transcripts (N = 12), three presented the wt/wt genotype and nine were SDF1-3'A carriers. Three of the latter were homozygous for this mutation. It is possible that the bcr-abl fusion gene and the SDF1 genotype for 3'A allele have important implications for the pathogenesis of CML." @default.
• W2014238497 created "2016-06-24" @default.
• W2014238497 creator A5021659769 @default.
• W2014238497 creator A5033758821 @default.
• W2014238497 creator A5034549758 @default.
• W2014238497 creator A5038684200 @default.
• W2014238497 creator A5040424175 @default.
• W2014238497 creator A5041804002 @default.
• W2014238497 creator A5051835963 @default.
• W2014238497 creator A5066300409 @default.
• W2014238497 date "2007-01-01" @default.
• W2014238497 modified "2023-10-14" @default.
• W2014238497 title "Stromal cell-derived factor-1 chemokine gene variant in blood donors and chronic myelogenous leukemia patients" @default.
• W2014238497 cites W115619992 @default.
• W2014238497 cites W1533139915 @default.
• W2014238497 cites W154306038 @default.
• W2014238497 cites W1917212660 @default.
• W2014238497 cites W1969130149 @default.
• W2014238497 cites W1983466424 @default.
• W2014238497 cites W2012348415 @default.
• W2014238497 cites W2014655794 @default.
• W2014238497 cites W2031807488 @default.
• W2014238497 cites W2038861087 @default.
• W2014238497 cites W2041053839 @default.
• W2014238497 cites W2060686995 @default.
• W2014238497 cites W2062862623 @default.
• W2014238497 cites W2067292278 @default.
• W2014238497 cites W2081769332 @default.
• W2014238497 cites W2098658264 @default.
• W2014238497 cites W2106915606 @default.
• W2014238497 cites W2131506926 @default.
• W2014238497 cites W2155139562 @default.
• W2014238497 cites W2157277269 @default.
• W2014238497 cites W2168746423 @default.
• W2014238497 cites W2169584423 @default.
• W2014238497 cites W2171248814 @default.
• W2014238497 cites W2396970895 @default.
• W2014238497 cites W2410606477 @default.
• W2014238497 cites W4245772308 @default.
• W2014238497 cites W2117710149 @default.
• W2014238497 doi "https://doi.org/10.1002/jcla.20142" @default.
• W2014238497 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6649230" @default.
• W2014238497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17245764" @default.
• W2014238497 hasPublicationYear "2007" @default.
• W2014238497 type Work @default.
• W2014238497 sameAs 2014238497 @default.
• W2014238497 citedByCount "28" @default.
• W2014238497 countsByYear W20142384972012 @default.
• W2014238497 countsByYear W20142384972013 @default.
• W2014238497 countsByYear W20142384972014 @default.
• W2014238497 countsByYear W20142384972015 @default.
• W2014238497 countsByYear W20142384972016 @default.
• W2014238497 countsByYear W20142384972017 @default.
• W2014238497 countsByYear W20142384972018 @default.
• W2014238497 crossrefType "journal-article" @default.
• W2014238497 hasAuthorship W2014238497A5021659769 @default.
• W2014238497 hasAuthorship W2014238497A5033758821 @default.
• W2014238497 hasAuthorship W2014238497A5034549758 @default.
• W2014238497 hasAuthorship W2014238497A5038684200 @default.
• W2014238497 hasAuthorship W2014238497A5040424175 @default.
• W2014238497 hasAuthorship W2014238497A5041804002 @default.
• W2014238497 hasAuthorship W2014238497A5051835963 @default.
• W2014238497 hasAuthorship W2014238497A5066300409 @default.
• W2014238497 hasBestOaLocation W20142384972 @default.
• W2014238497 hasConcept C104317684 @default.
• W2014238497 hasConcept C111829193 @default.
• W2014238497 hasConcept C125418893 @default.
• W2014238497 hasConcept C135763542 @default.
• W2014238497 hasConcept C16930146 @default.
• W2014238497 hasConcept C203014093 @default.
• W2014238497 hasConcept C2776960273 @default.
• W2014238497 hasConcept C2778461978 @default.
• W2014238497 hasConcept C2780007613 @default.
• W2014238497 hasConcept C28328180 @default.
• W2014238497 hasConcept C42362537 @default.
• W2014238497 hasConcept C502942594 @default.
• W2014238497 hasConcept C54355233 @default.
• W2014238497 hasConcept C62478195 @default.
• W2014238497 hasConcept C86803240 @default.
• W2014238497 hasConceptScore W2014238497C104317684 @default.
• W2014238497 hasConceptScore W2014238497C111829193 @default.
• W2014238497 hasConceptScore W2014238497C125418893 @default.
• W2014238497 hasConceptScore W2014238497C135763542 @default.
• W2014238497 hasConceptScore W2014238497C16930146 @default.
• W2014238497 hasConceptScore W2014238497C203014093 @default.
• W2014238497 hasConceptScore W2014238497C2776960273 @default.
• W2014238497 hasConceptScore W2014238497C2778461978 @default.
• W2014238497 hasConceptScore W2014238497C2780007613 @default.
• W2014238497 hasConceptScore W2014238497C28328180 @default.
• W2014238497 hasConceptScore W2014238497C42362537 @default.
• W2014238497 hasConceptScore W2014238497C502942594 @default.
• W2014238497 hasConceptScore W2014238497C54355233 @default.
• W2014238497 hasConceptScore W2014238497C62478195 @default.
• W2014238497 hasConceptScore W2014238497C86803240 @default.
• W2014238497 hasIssue "1" @default.
• W2014238497 hasLocation W20142384971 @default.
• W2014238497 hasLocation W20142384972 @default.
• W2014238497 hasLocation W20142384973 @default.

• next