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• W2014244619 abstract "The activity-guided fractionation of sun ginseng (SG, heat processed Panax ginseng C. A. Meyer at 120 degrees C) was carried out to identify its main active hydroxyl radical (*OH) scavenging components. As a result, the n-BuOH fraction mainly consisting of ginsenosides showed the strongest activity. Of several ginsenosides of SG, the *OH scavenging activities of relatively high contents of 20(S)-Rg(3), 20(R)-Rg(3), Rk(1), and Rg(5) were compared. Rg(5) and 20(S)-Rg(3) showed strong *OH scavenging IC(50) values of 0.15 and 0.44 mM, respectively, and these activities were prominently higher than each of their respective isomers. Therefore, stereospecificity exists in the *OH scavenging activities of ginsenosides produced by heat processing. Especially, the double bond at carbon-20(22) or the OH group at carbon-20 geometrically close to OH at carbon-12 is thought to increase the *OH scavenging activity of ginsenosides." @default.
• W2014244619 created "2016-06-24" @default.
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• W2014244619 date "2006-10-01" @default.
• W2014244619 modified "2023-09-25" @default.
• W2014244619 title "Stereospecificity in hydroxyl radical scavenging activities of four ginsenosides produced by heat processing" @default.
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• W2014244619 doi "https://doi.org/10.1016/j.bmcl.2006.07.071" @default.
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