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• W2014246614 abstract "This work is to study the baicalin and its three analogs, baicalin, wogonoside, and wogonin, on the protective effect of neuron from oxygen-glucose deprivation (OGD) and toll-like receptor 2 (TLR2) expression in OGD damage. The results showed that baicalin and its three analogs did protect neurons from OGD damage and downregulated protein level of TLR2. D-Glucopyranosiduronic acid on site 7 in the structure played a core of cytotoxicity of these flavonoid analogs. The methoxyl group on carbon 8 of the structure had the relation with TLR2 protein expression, as well as the anti-inflammation. In addition, we detected caspase3 and antioxidation capability, to investigate the effect of four analogs on cell apoptosis and total antioxidation competence in OGD model." @default.
• W2014246614 created "2016-06-24" @default.
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• W2014246614 date "2012-01-01" @default.
• W2014246614 modified "2023-10-16" @default.
• W2014246614 title "Comparative Study of the Effect of Baicalin and Its Natural Analogs on Neurons with Oxygen and Glucose Deprivation Involving Innate Immune Reaction of TLR2/TNF<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>α</mml:mi></mml:math>" @default.
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• W2014246614 doi "https://doi.org/10.1155/2012/267890" @default.
• W2014246614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3321472" @default.
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