Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014252364> ?p ?o ?g. }
- W2014252364 endingPage "1289" @default.
- W2014252364 startingPage "1283" @default.
- W2014252364 abstract "One of the leading causes for the failure of dental composite restorations is secondary caries. Effectively inhibiting cariogenic biofilms and reducing secondary caries could extend the service life of composite restorations. Dental composites releasing antibacterial agents such as chlorhexidine (CHX) have shown biofilm-inhibitory efficacy, but they usually have poor physical and mechanical properties. Herein, we present a study of a new method to encapsulate and release CHX from dental composite using mesoporous silica nanoparticles (MSNs). SBA-15 MSNs were synthesized according to a reported procedure. CHX (62.9 wt%) was encapsulated into dried MSN from 0.3 M CHX ethanol solution. The dental composites containing 0% (control), 3%, 5%, and 6.3% CHX or the same amounts of CHX entrapped in MSN (denoted as CHX@MSN) were fabricated with methacrylate monomers and silanized glass fillers (CHX or CHX@MSN + glass filler particle = 70 wt%). The monomer mixture consisted of bisphenol A glycidyl methacrylate (BisGMA), hexanediol dimethacrylate (HDDMA), ethoxylated bisphenol A dimethacrylate (EBPADMA), and urethane dimethacrylates (UEDMA) at a weight ratio of 40:30:20:10. The composites were tested for CHX release and recharge, flexural strength and modulus (at 24 hr and 1 mo), surface roughness, in vitro wear, and antibacterial activity against Streptococcus mutans and Lactobacillus casei (in both planktonic growth and biofilm formation). The results showed that the composites with CHX@MSN largely retained mechanical properties and smooth surfaces and showed controlled release of CHX over a long time. In contrast, the composites with directly mixed CHX showed reduced mechanical properties, rough surfaces, and burst release of CHX in a short time. The composites with CHX either directly mixed or in MSN showed strong inhibition to S. mutans and L. casei. This research has demonstrated the successful application of MSNs as a novel nanotechnology in dental materials to inhibit oral biofilm without sacrificing materials’ mechanical properties and surface integrity." @default.
- W2014252364 created "2016-06-24" @default.
- W2014252364 creator A5002790592 @default.
- W2014252364 creator A5005507931 @default.
- W2014252364 creator A5030265815 @default.
- W2014252364 creator A5057127903 @default.
- W2014252364 creator A5057371969 @default.
- W2014252364 creator A5075047410 @default.
- W2014252364 creator A5079129705 @default.
- W2014252364 date "2014-10-15" @default.
- W2014252364 modified "2023-10-11" @default.
- W2014252364 title "Antibacterial Dental Composites with Chlorhexidine and Mesoporous Silica" @default.
- W2014252364 cites W110205212 @default.
- W2014252364 cites W1962786227 @default.
- W2014252364 cites W1992019954 @default.
- W2014252364 cites W1995041236 @default.
- W2014252364 cites W1998168868 @default.
- W2014252364 cites W1998444495 @default.
- W2014252364 cites W1998562278 @default.
- W2014252364 cites W2000552906 @default.
- W2014252364 cites W2007652828 @default.
- W2014252364 cites W2009901448 @default.
- W2014252364 cites W2013635792 @default.
- W2014252364 cites W2013721111 @default.
- W2014252364 cites W2031611268 @default.
- W2014252364 cites W2044490782 @default.
- W2014252364 cites W2048758113 @default.
- W2014252364 cites W2049208919 @default.
- W2014252364 cites W2052458935 @default.
- W2014252364 cites W2053082088 @default.
- W2014252364 cites W2055523859 @default.
- W2014252364 cites W2056949659 @default.
- W2014252364 cites W2057944577 @default.
- W2014252364 cites W2058705883 @default.
- W2014252364 cites W2069186808 @default.
- W2014252364 cites W2084337627 @default.
- W2014252364 cites W2088066866 @default.
- W2014252364 cites W2105766306 @default.
- W2014252364 cites W2108751260 @default.
- W2014252364 cites W2158255299 @default.
- W2014252364 cites W2161616012 @default.
- W2014252364 cites W2170906176 @default.
- W2014252364 doi "https://doi.org/10.1177/0022034514555143" @default.
- W2014252364 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4237641" @default.
- W2014252364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25319365" @default.
- W2014252364 hasPublicationYear "2014" @default.
- W2014252364 type Work @default.
- W2014252364 sameAs 2014252364 @default.
- W2014252364 citedByCount "134" @default.
- W2014252364 countsByYear W20142523642015 @default.
- W2014252364 countsByYear W20142523642016 @default.
- W2014252364 countsByYear W20142523642017 @default.
- W2014252364 countsByYear W20142523642018 @default.
- W2014252364 countsByYear W20142523642019 @default.
- W2014252364 countsByYear W20142523642020 @default.
- W2014252364 countsByYear W20142523642021 @default.
- W2014252364 countsByYear W20142523642022 @default.
- W2014252364 countsByYear W20142523642023 @default.
- W2014252364 crossrefType "journal-article" @default.
- W2014252364 hasAuthorship W2014252364A5002790592 @default.
- W2014252364 hasAuthorship W2014252364A5005507931 @default.
- W2014252364 hasAuthorship W2014252364A5030265815 @default.
- W2014252364 hasAuthorship W2014252364A5057127903 @default.
- W2014252364 hasAuthorship W2014252364A5057371969 @default.
- W2014252364 hasAuthorship W2014252364A5075047410 @default.
- W2014252364 hasAuthorship W2014252364A5079129705 @default.
- W2014252364 hasBestOaLocation W20142523642 @default.
- W2014252364 hasConcept C104779481 @default.
- W2014252364 hasConcept C132050475 @default.
- W2014252364 hasConcept C13965031 @default.
- W2014252364 hasConcept C159985019 @default.
- W2014252364 hasConcept C161790260 @default.
- W2014252364 hasConcept C166940927 @default.
- W2014252364 hasConcept C178790620 @default.
- W2014252364 hasConcept C185592680 @default.
- W2014252364 hasConcept C192562407 @default.
- W2014252364 hasConcept C199343813 @default.
- W2014252364 hasConcept C2777084678 @default.
- W2014252364 hasConcept C2777496208 @default.
- W2014252364 hasConcept C2777698675 @default.
- W2014252364 hasConcept C2778430296 @default.
- W2014252364 hasConcept C2780801859 @default.
- W2014252364 hasConcept C521977710 @default.
- W2014252364 hasConcept C523546767 @default.
- W2014252364 hasConcept C54355233 @default.
- W2014252364 hasConcept C71924100 @default.
- W2014252364 hasConcept C82776694 @default.
- W2014252364 hasConcept C86803240 @default.
- W2014252364 hasConceptScore W2014252364C104779481 @default.
- W2014252364 hasConceptScore W2014252364C132050475 @default.
- W2014252364 hasConceptScore W2014252364C13965031 @default.
- W2014252364 hasConceptScore W2014252364C159985019 @default.
- W2014252364 hasConceptScore W2014252364C161790260 @default.
- W2014252364 hasConceptScore W2014252364C166940927 @default.
- W2014252364 hasConceptScore W2014252364C178790620 @default.
- W2014252364 hasConceptScore W2014252364C185592680 @default.
- W2014252364 hasConceptScore W2014252364C192562407 @default.
- W2014252364 hasConceptScore W2014252364C199343813 @default.