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- W2014256989 abstract "The clinical use of lymphocytes engineered to express high affinity T-cell receptors (TCRs) specific for two broadly expressed tumor-associated antigens is strongly limited by MHC-restricted fratricide of lymphocytes and TCR-mediated killing of hematopoietic stem cells. Specific clinical applications must therefore be conceived to bypass these limitations." @default.
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- W2014256989 date "2013-01-01" @default.
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- W2014256989 title "Limitations for TCR gene therapy by MHC-restricted fratricide and TCR-mediated hematopoietic stem cell toxicity" @default.
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- W2014256989 doi "https://doi.org/10.4161/onci.22410" @default.
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