Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014260701> ?p ?o ?g. }
- W2014260701 endingPage "578" @default.
- W2014260701 startingPage "565" @default.
- W2014260701 abstract "Semaphorins provide signals that guide growing axons to their appropriate destinations. The secreted semaphorin, Sema3A, mediates repulsive effects on axons from various neuronal populations in embryonic rats. The authors localized Sema3A mRNA expression in the primary olfactory pathway during development, in adult rats, and in adult rats that were subjected to a unilateral olfactory bulbectomy. Developing rats at ages from embryonic day 14 (E14) to E19 expressed Sema3A in the olfactory receptor neurons (ORNs) of the olfactory epithelium and in chondrogenic structures surrounding the nasal cavity. In vitro, ORN axons at E14 avoided substrate-bound Sema3A. Low levels of Sema3A expression persisted in the normal adult epithelium both in ORNs scattered throughout the epithelium and in small clusters. Three days after a unilateral olfactory bulbectomy, Sema3A transcript levels increased in regenerating neurons. High levels of Sema3A transcript were found at 1 week postbulbectomy, persisted for 2 weeks, and diminished by 3 weeks. Several other murine semaphorins (Sema4A, Sema4B, and Sema4C) were expressed differentially in the primary olfactory pathway both during development and regeneration. These findings suggest that Sema3A and perhaps other semaphorins play a role in directing ORNs out of the epithelium and to the olfactory bulb, their target structure, during both development and regeneration. J. Comp. Neurol. 423:565–578, 2000. © 2000 Wiley-Liss, Inc." @default.
- W2014260701 created "2016-06-24" @default.
- W2014260701 creator A5011022093 @default.
- W2014260701 creator A5029501084 @default.
- W2014260701 creator A5039084536 @default.
- W2014260701 creator A5040295133 @default.
- W2014260701 creator A5055708034 @default.
- W2014260701 creator A5066952714 @default.
- W2014260701 creator A5079861863 @default.
- W2014260701 creator A5091834202 @default.
- W2014260701 date "2000-01-01" @default.
- W2014260701 modified "2023-10-10" @default.
- W2014260701 title "Expression of semaphorins in developing and regenerating olfactory epithelium" @default.
- W2014260701 cites W1524612873 @default.
- W2014260701 cites W1678001779 @default.
- W2014260701 cites W1748993273 @default.
- W2014260701 cites W1765469392 @default.
- W2014260701 cites W1867551029 @default.
- W2014260701 cites W1965405861 @default.
- W2014260701 cites W1966792643 @default.
- W2014260701 cites W1968566156 @default.
- W2014260701 cites W1972627050 @default.
- W2014260701 cites W1973150820 @default.
- W2014260701 cites W1973548001 @default.
- W2014260701 cites W1975781078 @default.
- W2014260701 cites W1987868279 @default.
- W2014260701 cites W1990983421 @default.
- W2014260701 cites W1992639694 @default.
- W2014260701 cites W2002250124 @default.
- W2014260701 cites W2003766638 @default.
- W2014260701 cites W2010303364 @default.
- W2014260701 cites W2013184812 @default.
- W2014260701 cites W2013512584 @default.
- W2014260701 cites W2023193192 @default.
- W2014260701 cites W2031912570 @default.
- W2014260701 cites W2035588887 @default.
- W2014260701 cites W2036562186 @default.
- W2014260701 cites W2041700814 @default.
- W2014260701 cites W2046360665 @default.
- W2014260701 cites W2052856875 @default.
- W2014260701 cites W2054948590 @default.
- W2014260701 cites W2056836150 @default.
- W2014260701 cites W2057277074 @default.
- W2014260701 cites W2065668335 @default.
- W2014260701 cites W2068599628 @default.
- W2014260701 cites W2071877947 @default.
- W2014260701 cites W2077515896 @default.
- W2014260701 cites W2078833131 @default.
- W2014260701 cites W2109210857 @default.
- W2014260701 cites W2118999426 @default.
- W2014260701 cites W2124613558 @default.
- W2014260701 cites W4249871697 @default.
- W2014260701 cites W962147124 @default.
- W2014260701 doi "https://doi.org/10.1002/1096-9861(20000807)423:4<565::aid-cne3>3.0.co;2-f" @default.
- W2014260701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10880988" @default.
- W2014260701 hasPublicationYear "2000" @default.
- W2014260701 type Work @default.
- W2014260701 sameAs 2014260701 @default.
- W2014260701 citedByCount "40" @default.
- W2014260701 countsByYear W20142607012012 @default.
- W2014260701 countsByYear W20142607012014 @default.
- W2014260701 countsByYear W20142607012015 @default.
- W2014260701 countsByYear W20142607012021 @default.
- W2014260701 crossrefType "journal-article" @default.
- W2014260701 hasAuthorship W2014260701A5011022093 @default.
- W2014260701 hasAuthorship W2014260701A5029501084 @default.
- W2014260701 hasAuthorship W2014260701A5039084536 @default.
- W2014260701 hasAuthorship W2014260701A5040295133 @default.
- W2014260701 hasAuthorship W2014260701A5055708034 @default.
- W2014260701 hasAuthorship W2014260701A5066952714 @default.
- W2014260701 hasAuthorship W2014260701A5079861863 @default.
- W2014260701 hasAuthorship W2014260701A5091834202 @default.
- W2014260701 hasConcept C105702510 @default.
- W2014260701 hasConcept C132538176 @default.
- W2014260701 hasConcept C169760540 @default.
- W2014260701 hasConcept C170493617 @default.
- W2014260701 hasConcept C201792869 @default.
- W2014260701 hasConcept C2776805952 @default.
- W2014260701 hasConcept C2776886281 @default.
- W2014260701 hasConcept C2779980732 @default.
- W2014260701 hasConcept C2780187430 @default.
- W2014260701 hasConcept C2780496858 @default.
- W2014260701 hasConcept C529278444 @default.
- W2014260701 hasConcept C55493867 @default.
- W2014260701 hasConcept C86803240 @default.
- W2014260701 hasConcept C95444343 @default.
- W2014260701 hasConceptScore W2014260701C105702510 @default.
- W2014260701 hasConceptScore W2014260701C132538176 @default.
- W2014260701 hasConceptScore W2014260701C169760540 @default.
- W2014260701 hasConceptScore W2014260701C170493617 @default.
- W2014260701 hasConceptScore W2014260701C201792869 @default.
- W2014260701 hasConceptScore W2014260701C2776805952 @default.
- W2014260701 hasConceptScore W2014260701C2776886281 @default.
- W2014260701 hasConceptScore W2014260701C2779980732 @default.
- W2014260701 hasConceptScore W2014260701C2780187430 @default.
- W2014260701 hasConceptScore W2014260701C2780496858 @default.
- W2014260701 hasConceptScore W2014260701C529278444 @default.
- W2014260701 hasConceptScore W2014260701C55493867 @default.