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• W2014264295 abstract "A simple and efficient AlCl3-mediated C−C coupling reaction between readily available α-hydroxyketene-S,S-acetals and various arenes via direct substitution of the hydroxy group in alcohols has been developed. On the basis of this C−C coupling reaction, a series of bio- and pharmacologically important 3,4-disubstituted dihydrocoumarins, difficult to obtain by other methods, were prepared in high yields by a sequential Friedel−Crafts alkylation and intramolecular annulation reaction of α-hydroxyketene acyclic-S,S-acetals with phenols under mild conditions." @default.
• W2014264295 created "2016-06-24" @default.
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• W2014264295 date "2008-02-22" @default.
• W2014264295 modified "2023-09-27" @default.
• W2014264295 title "AlCl₃-Mediated Direct Carbon−Carbon Bond-Forming Reaction of α-Hydroxyketene-<i>S</i>,<i>S</i>-acetals with Arenes and Synthesis of 3,4-Disubstituted Dihydrocoumarin Derivatives" @default.
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• W2014264295 doi "https://doi.org/10.1021/jo702414y" @default.
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