Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014266902> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2014266902 endingPage "166" @default.
- W2014266902 startingPage "163" @default.
- W2014266902 abstract "The enzyme human carbonic anhydrase II (hCAII) crystallized in an acetate-bound complex belonging to space group P2(1)2(1)2(1), with unit-cell parameters a = 42.3, b = 71.8, c = 74.0 A. The structure was solved by the molecular-replacement method and refined to an R value of 0.18 and an R(free) of 0.21. The acetate molecule replaced the zinc-bound water molecule in the structure, differing from previous reports regarding the site of acetate binding. This mode of binding disrupts the hydrogen-bonded solvent network required for activity of the enzyme. This mode of inhibitor binding is a novel one that has not been observed previously." @default.
- W2014266902 created "2016-06-24" @default.
- W2014266902 creator A5002108565 @default.
- W2014266902 creator A5007472894 @default.
- W2014266902 creator A5040892915 @default.
- W2014266902 creator A5075327940 @default.
- W2014266902 date "2008-02-23" @default.
- W2014266902 modified "2023-09-27" @default.
- W2014266902 title "A novel acetate-bound complex of human carbonic anhydrase II" @default.
- W2014266902 cites W1539796472 @default.
- W2014266902 cites W1986191025 @default.
- W2014266902 cites W2028231353 @default.
- W2014266902 cites W2071155271 @default.
- W2014266902 cites W2073618740 @default.
- W2014266902 cites W2080528351 @default.
- W2014266902 cites W2083361076 @default.
- W2014266902 cites W2088350865 @default.
- W2014266902 cites W2097493124 @default.
- W2014266902 cites W2139942857 @default.
- W2014266902 cites W2397681412 @default.
- W2014266902 cites W255996521 @default.
- W2014266902 doi "https://doi.org/10.1107/s1744309108002078" @default.
- W2014266902 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2374158" @default.
- W2014266902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18323598" @default.
- W2014266902 hasPublicationYear "2008" @default.
- W2014266902 type Work @default.
- W2014266902 sameAs 2014266902 @default.
- W2014266902 citedByCount "9" @default.
- W2014266902 countsByYear W20142669022012 @default.
- W2014266902 countsByYear W20142669022015 @default.
- W2014266902 countsByYear W20142669022017 @default.
- W2014266902 countsByYear W20142669022019 @default.
- W2014266902 countsByYear W20142669022020 @default.
- W2014266902 crossrefType "journal-article" @default.
- W2014266902 hasAuthorship W2014266902A5002108565 @default.
- W2014266902 hasAuthorship W2014266902A5007472894 @default.
- W2014266902 hasAuthorship W2014266902A5040892915 @default.
- W2014266902 hasAuthorship W2014266902A5075327940 @default.
- W2014266902 hasBestOaLocation W20142669022 @default.
- W2014266902 hasConcept C107824862 @default.
- W2014266902 hasConcept C178790620 @default.
- W2014266902 hasConcept C181199279 @default.
- W2014266902 hasConcept C185592680 @default.
- W2014266902 hasConcept C2775914622 @default.
- W2014266902 hasConcept C2780416268 @default.
- W2014266902 hasConcept C2780471494 @default.
- W2014266902 hasConcept C32909587 @default.
- W2014266902 hasConcept C535196362 @default.
- W2014266902 hasConcept C55493867 @default.
- W2014266902 hasConcept C71240020 @default.
- W2014266902 hasConcept C73673656 @default.
- W2014266902 hasConcept C8010536 @default.
- W2014266902 hasConceptScore W2014266902C107824862 @default.
- W2014266902 hasConceptScore W2014266902C178790620 @default.
- W2014266902 hasConceptScore W2014266902C181199279 @default.
- W2014266902 hasConceptScore W2014266902C185592680 @default.
- W2014266902 hasConceptScore W2014266902C2775914622 @default.
- W2014266902 hasConceptScore W2014266902C2780416268 @default.
- W2014266902 hasConceptScore W2014266902C2780471494 @default.
- W2014266902 hasConceptScore W2014266902C32909587 @default.
- W2014266902 hasConceptScore W2014266902C535196362 @default.
- W2014266902 hasConceptScore W2014266902C55493867 @default.
- W2014266902 hasConceptScore W2014266902C71240020 @default.
- W2014266902 hasConceptScore W2014266902C73673656 @default.
- W2014266902 hasConceptScore W2014266902C8010536 @default.
- W2014266902 hasIssue "3" @default.
- W2014266902 hasLocation W20142669021 @default.
- W2014266902 hasLocation W20142669022 @default.
- W2014266902 hasLocation W20142669023 @default.
- W2014266902 hasLocation W20142669024 @default.
- W2014266902 hasOpenAccess W2014266902 @default.
- W2014266902 hasPrimaryLocation W20142669021 @default.
- W2014266902 hasRelatedWork W1531700958 @default.
- W2014266902 hasRelatedWork W1971387475 @default.
- W2014266902 hasRelatedWork W2004696629 @default.
- W2014266902 hasRelatedWork W2024000860 @default.
- W2014266902 hasRelatedWork W2049301530 @default.
- W2014266902 hasRelatedWork W2091838847 @default.
- W2014266902 hasRelatedWork W2952804851 @default.
- W2014266902 hasRelatedWork W3112269243 @default.
- W2014266902 hasRelatedWork W4250301000 @default.
- W2014266902 hasRelatedWork W3178245966 @default.
- W2014266902 hasVolume "64" @default.
- W2014266902 isParatext "false" @default.
- W2014266902 isRetracted "false" @default.
- W2014266902 magId "2014266902" @default.
- W2014266902 workType "article" @default.