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- W2014270953 abstract "Intracellular Na+ activities and local current densities were measured in fused Madin-Darby canine kidney cells using Na+ and voltage-sensing microelectrodes. Na+ that enters the cell across the apical plasma membrane accumulates initially in the nucleoplasm, several seconds ahead of its appearance in the cell cytoplasm. The spatial distribution of Na+ currents, produced by a local superfusion of the cell surface, indicates a nonuniform, patchy accumulation of apical Na+ transporters in the vicinity of the nucleus. Such pathways for direct Na+ flux between extracellular space and cell nucleus could be potentially important for gene activation." @default.
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- W2014270953 title "Patchy accumulation of apical Na+ transporters allows cross talk between extracellular space and cell nucleus." @default.
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- W2014270953 doi "https://doi.org/10.1073/pnas.89.1.241" @default.
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