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- W2014286101 abstract "Abstract Radioiodinated soluble fibrin, a derivative of radioiodinated fibrinogen, has been investigated for thrombus localization. Soluble fibrin can be labeled with 123 I as the radionuclide for imaging thrombi with a scintillation camera. Protein iodination grade 123 I is produced by a distillation and extraction procedure from the product of the 121 Sb ( α , 2 n ) 123 I reaction in the Washington University 54-in. cyclotron. Labeling with these 123 I preparation is effected by the iodine monochloride method. Induced 4–6-hr-old femoral vein thrombi in dogs can be visualized beginning 2 hr after injection of 1 mCi of 123 I-labeled soluble fibrin. This new radiopharmaceutical may be useful for imaging actively-propagating thrombi in patients, especially in areas of large blood pool. Its potential appears to be similar to that of 123 I-labeled highly iodinated fibrinogen, another new thrombus imaging agent." @default.
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- W2014286101 date "1977-01-01" @default.
- W2014286101 modified "2023-09-23" @default.
- W2014286101 title "123I-labeled soluble fibrin: Preparation and comparison with other thrombus imaging agents" @default.
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- W2014286101 doi "https://doi.org/10.1016/0020-708x(77)90169-7" @default.
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