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- W2014287178 abstract "The Journal of Clinical PharmacologyVolume 18, Issue 5-6 p. 272-279 Indomethacin Disposition and Indomethacin-Induced Platelet Dysfunction in Premature Infants Dr. ZVI FRIEDMAN M.D., F.R.C.P.(C), Corresponding Author Dr. ZVI FRIEDMAN M.D., F.R.C.P.(C) Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Department of Pediatrics, The Milton S. Hershey Medical Center, Hershey, Penn. 17033.Search for more papers by this authorVICTOR WHITMAN M.D., VICTOR WHITMAN M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorM. JEFFREY MAISELS M.B., B.Ch., M. JEFFREY MAISELS M.B., B.Ch. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorWILLIAM BERMAN JR. M.D., WILLIAM BERMAN JR. M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorKEITH H MARKS M.B., F.C.P., KEITH H MARKS M.B., F.C.P. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorELLIOT S. VESELL M.D., ELLIOT S. VESELL M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this author Dr. ZVI FRIEDMAN M.D., F.R.C.P.(C), Corresponding Author Dr. ZVI FRIEDMAN M.D., F.R.C.P.(C) Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Department of Pediatrics, The Milton S. Hershey Medical Center, Hershey, Penn. 17033.Search for more papers by this authorVICTOR WHITMAN M.D., VICTOR WHITMAN M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorM. JEFFREY MAISELS M.B., B.Ch., M. JEFFREY MAISELS M.B., B.Ch. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorWILLIAM BERMAN JR. M.D., WILLIAM BERMAN JR. M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorKEITH H MARKS M.B., F.C.P., KEITH H MARKS M.B., F.C.P. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this authorELLIOT S. VESELL M.D., ELLIOT S. VESELL M.D. Departments of Pediatrics and Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Penn. 17033.Search for more papers by this author First published: May‐June 1978 https://doi.org/10.1002/j.1552-4604.1978.tb02446.xCitations: 62AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Friedman, W. F., Kirschklau, M. J., Printz, M. P., Pitlick, P. T., and Kirkpatrick, S. E.: Pharmacologic closure of patent ductus arteriosus in the premature infant. New England J. Med. 295: 526 (1976). 2 Heymann, M. A., Rudolph, A. M., and Silverman, N. H.: Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis. New England J. Med. 295: 530 (1976). 3 Elliott, R. B., Starling, M. B., and Neutze, J. M.: Medical manipulation of the ductus arteriosus. Lancet 1: 140 (1975). 4 Olley, P. M., Coceani, F., and Bodach, E.: E-Type prostaglandins. A new emergency therapy for certain cyanotic congenital heart malformations. Circulation 53: 728 (1976). 5 Traeger, A., Nöschel, H., and Zaumseil, J.: Zur Pharmakokinetik von Indomethazin bei Schwangeren, Kreissenden und deren Neugeborenen. Zantralbl. Gynaekol. 95: 635 (1973). 6 Silverman, N. H., Lewis, A. B., Heymann, M. A., and Rudolph, A. M.: Echocardiographic assessment of ductus arteriosus in premature infants. Circulation 50: 821 (1974). 7 Breault, G. O., and Demetriades, J.: A gas chromatographic method for determination of indomethacin in plasma and urine. American Institute for Therapeutic Research, West Point, Pa., to be published. 8 Ferry, D. G., Ferry, D. M., Moller, P. W., and McQueen, E. G.: Indomethacin estimation in plasma and serum by electron capture gas chromatography. J. Chromatogr. 89: 110 (1974). 9 Helleberg, L.: Determination of indomethacin in serum and urine by electron capture gas liquid chromatography. J. Chromatogr. 117: 167 (1976). 10 Friedman, Z., Lamberth, E. L., Stahlman, M. T., and Oates, J. A.: Platelet dysfunction in the neonate with essential fatty acid deficiency. J. Pediat. 90: 439 (1977). 11 Minsker, D. H., Humes, J. L., Jordan, P. T., Kling, P. J., and Wolf, G. L.: Prostaglandin synthetase inhibitors as antithrombotic agents. In Prostaglandins in Hematology, M. H. Silver, J. B. Smith, and J. J. Kocsis Eds. New York, Spectrum Publications, 1977, p. 331. 12 Neal, W. A., Kyle, J. M., and Mullett, M. D.: Failure of indomethacin therapy to induce closure of patent ductus arteriosus in premature infants with respiratory distress syndrome. J. Pediat. 91: 621 (1977). 13 Hucker, H. B., Zacchei, A. G., Cox, S. V., Brodie, D. A., and Cantwell, N. H. R.: Studies on the absorption, distribution and excretion of indomethacin in various species. J. Pharmacol. Exp. Therap. 153: 237 (1966). 14 Duggan, D. A., Hogans, A. F., Kwan, K. C., and McMahon, F. G.: The metabolism of indomethacin in man. J. Pharmacol. Exp. Therap. 181: 563 (1972). 15 Palmer, L., Bertilsson, L., Alvan, G., Orme, M., Sjöqvist, F., and Holmstedt, B. O.: Indomethacin: quantitative determination in plasma by mass fragmentography including pilot pharmacokinetics in man. In Prostaglandin Synthetase Inhibitors, H. J. Robinson, and J. R. Vane Eds. New York, Raven Press, 1974, p. 91. 16 Brown, A. K., Zeulzer, W. W., and Burnett, H. H.: Studies on the neonatal development of the glucuronide conjugating system. J. Clin. Invest. 37: 332 (1958). 17 Guignard, J. P., Torrado, A., Da Cunha, O., and Gautier, E.: Glomerular filtration rate in the first three weeks of life. J. Pediat. 87: 268 (1975). 18 Friedman, W. F., Heymann, M. A., and Rudolph, A. M.: Commentary: new thoughts on an old problem—patent ductus arteriosus in the premature infant. J. Pediat. 90: 338 (1977). 19 Rudolph, A. M., and Heymann, M. A.: Medical treatment of the ductus arteriosus. Hospital Practice 12: 57 (Feb. 1977). 20 Samuelsson, B., Hamberg, M., Malmsten, C., and Svensson, J.: The role of prostaglandin endoperoxides and thromboxanes in platelet aggregation. In Advances in Prostaglandin and Thromboxane Research, B. Samuelsson, and R. Paoletti Eds. New York, Raven Press, 1976. 21 Smith, J. B., Ingerman, C. M., and Silver, M. J.: Platelet prostaglandin production and its implications. In Advances in Prostaglandin and Thromboxane Research, B. Samuelsson, and R. Paoletti Eds. New York, Raven Press, 1976, p. 747. Citing Literature Volume18, Issue5-6May‐June 1978Pages 272-279 ReferencesRelatedInformation" @default.
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