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- W2014291610 abstract "The blocking action of alpha-polypeptides from the venoms of elapid snakes (Bungarus multicinctus and Naja naja siamensis) was studied on leech dorsal muscle. It was shown that these neurotoxins failed to inhibit the responses to mononitrogen cholinomimetics (acetylcholine, nicotine, carbamylcholine, etc.). The capacity of neurotoxins to inhibit the responses to the bisquaternary cholinommimetics depended upon the length of the molecule. The neurotoxins were active against the shorter cholinomimetics, such as decamethonium, and bischolinic esters of malonic, succinic and glutaric acids. The longer cholinomimetics (bischolinic esters of adipinic, pimelic, suberic, azelaic, sebacic acids retained their full activity after the treatment of leech dorsal muscle by neurotoxins. Possible explanations of the selective action of neurotoxins are discussed." @default.
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- W2014291610 title "[The blocking action of snake venom polypeptides on the cholinergic mechanisms of leech dorsal muscle]." @default.
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