FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014297777> ?p ?o ?g. }

• W2014297777 endingPage "2655" @default.
• W2014297777 startingPage "2650" @default.
• W2014297777 abstract "Nanoporous materials with different pore sizes are evaluated as immobilization and stabilization matrices of proteins for the development of highly stable biosensors. It has been proven experimentally that confinement of proteins in cages with a diameter that is 2-6 times larger than their size increases considerably the stability of the biomolecules, as has been shown earlier by theoretical calculations. Porous silica beads with pore sizes of 10nm were utilized for the immobilization of the enzymes HRP and GOx with diameters in the order of 5 and 7 nm, respectively. The sensitivity of the corresponding biosensor systems was monitored for 70 h under continuous operation conditions (+600 mV) and it was found that the stabilization factor of GOx is 1.7 times higher compared to HRP. Also the stabilization efficiency of enzymes against leaching and inactivation in porous polymer beads with pore diameters of 10 and 30 nm was examined. The leaching rate of the enzyme AChE from the 30 nm polymer beads was found to be 1.1 times higher than that from the 10nm beads. At the same time the remaining activity of GOx biosensors after 5 days of continuous operation conditions (+600 mV) was found to be 2.1 times higher when the enzyme had been immobilized in the 10nm beads compared to the 30 nm beads. It is thus evident that the matching between the pore size of nanoporous materials and the molecular size of enzymes is essential for the development of biosensors with extended shelf and operational lifetimes." @default.
• W2014297777 created "2016-06-24" @default.
• W2014297777 creator A5006445802 @default.
• W2014297777 creator A5034104175 @default.
• W2014297777 date "2007-05-01" @default.
• W2014297777 modified "2023-09-30" @default.
• W2014297777 title "Immobilization of enzymes into nanocavities for the improvement of biosensor stability" @default.
• W2014297777 cites W1968396647 @default.
• W2014297777 cites W1971048984 @default.
• W2014297777 cites W1981257555 @default.
• W2014297777 cites W1987330726 @default.
• W2014297777 cites W2000332345 @default.
• W2014297777 cites W2001763975 @default.
• W2014297777 cites W2014699872 @default.
• W2014297777 cites W2020186943 @default.
• W2014297777 cites W2032173425 @default.
• W2014297777 cites W2041161170 @default.
• W2014297777 cites W2057125392 @default.
• W2014297777 cites W2060654656 @default.
• W2014297777 cites W2062110094 @default.
• W2014297777 cites W2065571647 @default.
• W2014297777 cites W2068398493 @default.
• W2014297777 cites W2078139254 @default.
• W2014297777 cites W2078864635 @default.
• W2014297777 cites W2083494369 @default.
• W2014297777 cites W2085238030 @default.
• W2014297777 cites W2086926494 @default.
• W2014297777 cites W2088420689 @default.
• W2014297777 cites W2099264016 @default.
• W2014297777 cites W2100601849 @default.
• W2014297777 cites W2122802861 @default.
• W2014297777 cites W3099624231 @default.
• W2014297777 cites W4239883860 @default.
• W2014297777 doi "https://doi.org/10.1016/j.bios.2006.10.040" @default.
• W2014297777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17142036" @default.
• W2014297777 hasPublicationYear "2007" @default.
• W2014297777 type Work @default.
• W2014297777 sameAs 2014297777 @default.
• W2014297777 citedByCount "50" @default.
• W2014297777 countsByYear W20142977772012 @default.
• W2014297777 countsByYear W20142977772013 @default.
• W2014297777 countsByYear W20142977772014 @default.
• W2014297777 countsByYear W20142977772015 @default.
• W2014297777 countsByYear W20142977772016 @default.
• W2014297777 countsByYear W20142977772017 @default.
• W2014297777 countsByYear W20142977772018 @default.
• W2014297777 countsByYear W20142977772019 @default.
• W2014297777 countsByYear W20142977772020 @default.
• W2014297777 countsByYear W20142977772021 @default.
• W2014297777 crossrefType "journal-article" @default.
• W2014297777 hasAuthorship W2014297777A5006445802 @default.
• W2014297777 hasAuthorship W2014297777A5034104175 @default.
• W2014297777 hasConcept C108586683 @default.
• W2014297777 hasConcept C127413603 @default.
• W2014297777 hasConcept C159390177 @default.
• W2014297777 hasConcept C159750122 @default.
• W2014297777 hasConcept C159985019 @default.
• W2014297777 hasConcept C160756335 @default.
• W2014297777 hasConcept C171250308 @default.
• W2014297777 hasConcept C178790620 @default.
• W2014297777 hasConcept C181199279 @default.
• W2014297777 hasConcept C185592680 @default.
• W2014297777 hasConcept C188027245 @default.
• W2014297777 hasConcept C192562407 @default.
• W2014297777 hasConcept C33633552 @default.
• W2014297777 hasConcept C39432304 @default.
• W2014297777 hasConcept C42360764 @default.
• W2014297777 hasConcept C43617362 @default.
• W2014297777 hasConcept C48940184 @default.
• W2014297777 hasConcept C49853544 @default.
• W2014297777 hasConcept C521977710 @default.
• W2014297777 hasConcept C6648577 @default.
• W2014297777 hasConcept C90982505 @default.
• W2014297777 hasConceptScore W2014297777C108586683 @default.
• W2014297777 hasConceptScore W2014297777C127413603 @default.
• W2014297777 hasConceptScore W2014297777C159390177 @default.
• W2014297777 hasConceptScore W2014297777C159750122 @default.
• W2014297777 hasConceptScore W2014297777C159985019 @default.
• W2014297777 hasConceptScore W2014297777C160756335 @default.
• W2014297777 hasConceptScore W2014297777C171250308 @default.
• W2014297777 hasConceptScore W2014297777C178790620 @default.
• W2014297777 hasConceptScore W2014297777C181199279 @default.
• W2014297777 hasConceptScore W2014297777C185592680 @default.
• W2014297777 hasConceptScore W2014297777C188027245 @default.
• W2014297777 hasConceptScore W2014297777C192562407 @default.
• W2014297777 hasConceptScore W2014297777C33633552 @default.
• W2014297777 hasConceptScore W2014297777C39432304 @default.
• W2014297777 hasConceptScore W2014297777C42360764 @default.
• W2014297777 hasConceptScore W2014297777C43617362 @default.
• W2014297777 hasConceptScore W2014297777C48940184 @default.
• W2014297777 hasConceptScore W2014297777C49853544 @default.
• W2014297777 hasConceptScore W2014297777C521977710 @default.
• W2014297777 hasConceptScore W2014297777C6648577 @default.
• W2014297777 hasConceptScore W2014297777C90982505 @default.
• W2014297777 hasFunder F4320320300 @default.
• W2014297777 hasFunder F4320323846 @default.
• W2014297777 hasIssue "11" @default.
• W2014297777 hasLocation W20142977771 @default.

• next