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- W2014299957 abstract "Pantoprazole (1), a substituted benzimidazole derivative, is an irreversible proton pump inhibitor, essentially used for the prevention and treatment of gastric acid-related diseases. The process for its preparation generally suffers from the drawback of producing a potential sulfone impurity (5). The present work details a report of the journey towards the development of a simple, single-pot process for the production of pantoprazole, substantially free from sulfone impurity (5). The detailed study of the different parameters affecting the purity and yield of the compound has been presented." @default.
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- W2014299957 date "2004-03-01" @default.
- W2014299957 modified "2023-09-25" @default.
- W2014299957 title "An Improved and Single-Pot Process for the Production of Pantoprazole Substantially Free from Sulfone Impurity" @default.
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- W2014299957 doi "https://doi.org/10.1021/op034157y" @default.
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