FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014303847> ?p ?o ?g. }

• W2014303847 endingPage "224" @default.
• W2014303847 startingPage "224" @default.
• W2014303847 abstract "See Article on Page 252-265Accurate tumor staging is an essential step for the management of colorectal cancer patients. Precise tumor staging has a pivotal role not only for the prediction of the patient's prognosis, but also for the selection of patients for adjuvant therapy. The Tumor-node-metastasis (TNM) staging system based on pathologic findings is the most popular staging system in clinical practice.Among several prognosticators in TNM staging, the presence of regional lymph-node metastasis is the most potent indicator of the patient's prognosis in cases of colorectal cancer. In the current staging system, nodal stage is classified by the number of metastatic lymph nodes. In addition, several studies have reported that the number of retrieved lymph nodes also has prognostic power because a sufficient number of lymph nodes should be examined for accurate staging. For that reason, in the American Joint Committee on Cancer (AJCC) 7th edition recommends that at least 10-14 lymph nodes in radical colon and rectum resections should be examined for reliable nodal staging [1].The number of retrieved lymph nodes could be affected by the extent of surgery and the pertinacity of the pathologist, but the location of tumor, the application of preoperative radiotherapy, and patient factors, including body mass index, could also be contributing factors. Moreover, in cases of preoperative chemoradiation therapy, the proportion of those with fewer than 12 examined lymph nodes may be increased. Since a prerequisite for the current nodal staging is the examination of over 10-14 regional lymph nodes, nodal staging in stage III colorectal cancer, which is solely based on the number of metastatic lymph nodes, would be inaccurate in certain circumstances.Recently, the metastatic lymph-node ratio has been suggested as an alternative tool for nodal staging in stage III colorectal cancer [2-4]. Also, after preoperative chemoradiation therapy in rectal cancer patients, the lymph-node ratio has reportedly been able to provide better stratification of patients' prognoses than ypN staging [5]. A recent series of publications support the lymph-node ratio's being a successful substitute for the current nodal staging in overcoming the limitation of the numeric counting system in cases of colorectal cancer. However, there are still several problems in the studies regarding the lymph-node ratio.The biggest hurdle in nodal staging with the lymph-node ratio may be that there is no consensus on a point of reference for stratification. Even though the lymph-node ratio has shown very nice stratification of patients' prognoses in cases of stage III colorectal cancer, not all studies adapted the same point of reference. Standardization of the point of reference would be an essential step toward use of the lymph-node ratio in staging. There is no doubt that precise lymph-node staging would be an essential step toward providing accurate prognoses for colorectal cancer patients and selecting candidates for adjuvant therapy. Several studies have demonstrated the possibility of using the lymph-node ratio as a tool for more accurate nodal staging in colorectal cancer. However, many obstacles remain to be overcome before the acceptance of the lymph-node ratio in our daily practice." @default.
• W2014303847 created "2016-06-24" @default.
• W2014303847 creator A5088184916 @default.
• W2014303847 date "2011-01-01" @default.
• W2014303847 modified "2023-09-30" @default.
• W2014303847 title "Lymph Node Ratio for Nodal Staging in Colorectal Cancer - a Promising, but Premature Tool" @default.
• W2014303847 cites W1515127609 @default.
• W2014303847 cites W2043564561 @default.
• W2014303847 cites W2081679704 @default.
• W2014303847 cites W2082327705 @default.
• W2014303847 doi "https://doi.org/10.3393/jksc.2011.27.5.224" @default.
• W2014303847 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3218124" @default.
• W2014303847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22102970" @default.
• W2014303847 hasPublicationYear "2011" @default.
• W2014303847 type Work @default.
• W2014303847 sameAs 2014303847 @default.
• W2014303847 citedByCount "2" @default.
• W2014303847 countsByYear W20143038472014 @default.
• W2014303847 countsByYear W20143038472016 @default.
• W2014303847 crossrefType "journal-article" @default.
• W2014303847 hasAuthorship W2014303847A5088184916 @default.
• W2014303847 hasBestOaLocation W20143038471 @default.
• W2014303847 hasConcept C121608353 @default.
• W2014303847 hasConcept C126322002 @default.
• W2014303847 hasConcept C126838900 @default.
• W2014303847 hasConcept C142724271 @default.
• W2014303847 hasConcept C143998085 @default.
• W2014303847 hasConcept C146357865 @default.
• W2014303847 hasConcept C151730666 @default.
• W2014303847 hasConcept C2776808855 @default.
• W2014303847 hasConcept C2777982462 @default.
• W2014303847 hasConcept C2779013556 @default.
• W2014303847 hasConcept C2779720271 @default.
• W2014303847 hasConcept C2780091936 @default.
• W2014303847 hasConcept C2780325254 @default.
• W2014303847 hasConcept C2780849966 @default.
• W2014303847 hasConcept C2993415550 @default.
• W2014303847 hasConcept C509974204 @default.
• W2014303847 hasConcept C526805850 @default.
• W2014303847 hasConcept C71924100 @default.
• W2014303847 hasConcept C86803240 @default.
• W2014303847 hasConceptScore W2014303847C121608353 @default.
• W2014303847 hasConceptScore W2014303847C126322002 @default.
• W2014303847 hasConceptScore W2014303847C126838900 @default.
• W2014303847 hasConceptScore W2014303847C142724271 @default.
• W2014303847 hasConceptScore W2014303847C143998085 @default.
• W2014303847 hasConceptScore W2014303847C146357865 @default.
• W2014303847 hasConceptScore W2014303847C151730666 @default.
• W2014303847 hasConceptScore W2014303847C2776808855 @default.
• W2014303847 hasConceptScore W2014303847C2777982462 @default.
• W2014303847 hasConceptScore W2014303847C2779013556 @default.
• W2014303847 hasConceptScore W2014303847C2779720271 @default.
• W2014303847 hasConceptScore W2014303847C2780091936 @default.
• W2014303847 hasConceptScore W2014303847C2780325254 @default.
• W2014303847 hasConceptScore W2014303847C2780849966 @default.
• W2014303847 hasConceptScore W2014303847C2993415550 @default.
• W2014303847 hasConceptScore W2014303847C509974204 @default.
• W2014303847 hasConceptScore W2014303847C526805850 @default.
• W2014303847 hasConceptScore W2014303847C71924100 @default.
• W2014303847 hasConceptScore W2014303847C86803240 @default.
• W2014303847 hasIssue "5" @default.
• W2014303847 hasLocation W20143038471 @default.
• W2014303847 hasLocation W20143038472 @default.
• W2014303847 hasLocation W20143038473 @default.
• W2014303847 hasLocation W20143038474 @default.
• W2014303847 hasOpenAccess W2014303847 @default.
• W2014303847 hasPrimaryLocation W20143038471 @default.
• W2014303847 hasRelatedWork W1036854731 @default.
• W2014303847 hasRelatedWork W133802213 @default.
• W2014303847 hasRelatedWork W1966548854 @default.
• W2014303847 hasRelatedWork W2044765083 @default.
• W2014303847 hasRelatedWork W2074997808 @default.
• W2014303847 hasRelatedWork W2088733301 @default.
• W2014303847 hasRelatedWork W2089794718 @default.
• W2014303847 hasRelatedWork W2121483082 @default.
• W2014303847 hasRelatedWork W2135596536 @default.
• W2014303847 hasRelatedWork W2157424735 @default.
• W2014303847 hasRelatedWork W2167963079 @default.
• W2014303847 hasRelatedWork W2187356288 @default.
• W2014303847 hasRelatedWork W2224664471 @default.
• W2014303847 hasRelatedWork W2317810714 @default.
• W2014303847 hasRelatedWork W2515590077 @default.
• W2014303847 hasRelatedWork W2563672343 @default.
• W2014303847 hasRelatedWork W2590306544 @default.
• W2014303847 hasRelatedWork W2601384616 @default.
• W2014303847 hasRelatedWork W4519909 @default.
• W2014303847 hasRelatedWork W2086376969 @default.
• W2014303847 hasVolume "27" @default.
• W2014303847 isParatext "false" @default.
• W2014303847 isRetracted "false" @default.
• W2014303847 magId "2014303847" @default.
• W2014303847 workType "article" @default.