Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014320851> ?p ?o ?g. }
- W2014320851 endingPage "1613" @default.
- W2014320851 startingPage "1592" @default.
- W2014320851 abstract "Cigarette smoking has been causally linked several diseases, primarily lung cancer and chronic obstructive lung disease (COPD). The diagnosis of COPD currently involves an assessment of smoking and/or occupational exposures, a history of cough, sputum and dyspnea and spirometric measures of airflow obstruction and since spirometric measures take long follow up times to detect significant changes, surrogate measures of outcome capable of predicting long-term health changes have been sought for. These include biomarkers of oxidative stress, inflammation and tissue damage in sputum, bronchoalveolar lavage, exhaled breath and serum. Published biomarker studies have not always accurately compared patients with COPD with age-matched cigarette smokers and non-smoking normal subjects without significant airflow limitation, also comparable for other exposures. Consequently, the interpretation of biomarker association studies is somewhat difficult. The purpose of this narrative review is to summarize publications reporting cellular, soluble or volatile marker of obstructive lung disease in populations of healthy non-smokers and healthy smokers, in order to determine whether the biomarkers examined could be specifically associated with exposure to tobacco smoke rather than with inflammation and airway hyper-reactivity. As induced sputum has been the most widely used investigative tool, this review has been aimed at assessing induced sputum biomarkers, referring to lung biopsy, bronchoalveolar lavage and exhaled breath markers as supporting evidence for biomarkers associations identified with induced sputum studies." @default.
- W2014320851 created "2016-06-24" @default.
- W2014320851 creator A5031743354 @default.
- W2014320851 creator A5043696677 @default.
- W2014320851 creator A5053217610 @default.
- W2014320851 creator A5060089859 @default.
- W2014320851 creator A5060150892 @default.
- W2014320851 creator A5065290400 @default.
- W2014320851 date "2009-11-01" @default.
- W2014320851 modified "2023-09-25" @default.
- W2014320851 title "Biomarkers of lung damage associated with tobacco smoke in induced sputum" @default.
- W2014320851 cites W1892660313 @default.
- W2014320851 cites W1897453816 @default.
- W2014320851 cites W1963842234 @default.
- W2014320851 cites W1968853064 @default.
- W2014320851 cites W1969639414 @default.
- W2014320851 cites W1978434499 @default.
- W2014320851 cites W1979802926 @default.
- W2014320851 cites W1982006485 @default.
- W2014320851 cites W1985051240 @default.
- W2014320851 cites W1985211695 @default.
- W2014320851 cites W1985500792 @default.
- W2014320851 cites W1988449693 @default.
- W2014320851 cites W1988769263 @default.
- W2014320851 cites W1989935661 @default.
- W2014320851 cites W1990127385 @default.
- W2014320851 cites W1990674750 @default.
- W2014320851 cites W1991685549 @default.
- W2014320851 cites W1992940048 @default.
- W2014320851 cites W1995024650 @default.
- W2014320851 cites W1996040058 @default.
- W2014320851 cites W1999549209 @default.
- W2014320851 cites W1999964657 @default.
- W2014320851 cites W2002592975 @default.
- W2014320851 cites W2003564059 @default.
- W2014320851 cites W2004556227 @default.
- W2014320851 cites W2004635533 @default.
- W2014320851 cites W2006105457 @default.
- W2014320851 cites W2010240128 @default.
- W2014320851 cites W2012679834 @default.
- W2014320851 cites W2018265111 @default.
- W2014320851 cites W2019140140 @default.
- W2014320851 cites W2019449022 @default.
- W2014320851 cites W2020585064 @default.
- W2014320851 cites W2023018801 @default.
- W2014320851 cites W2023662838 @default.
- W2014320851 cites W2023784559 @default.
- W2014320851 cites W2025136858 @default.
- W2014320851 cites W2026421616 @default.
- W2014320851 cites W2028782063 @default.
- W2014320851 cites W2029146675 @default.
- W2014320851 cites W2030294191 @default.
- W2014320851 cites W2032558482 @default.
- W2014320851 cites W2033380992 @default.
- W2014320851 cites W2033713843 @default.
- W2014320851 cites W2034662757 @default.
- W2014320851 cites W2035657747 @default.
- W2014320851 cites W2039027028 @default.
- W2014320851 cites W2039172942 @default.
- W2014320851 cites W2040099837 @default.
- W2014320851 cites W2040821832 @default.
- W2014320851 cites W2042797839 @default.
- W2014320851 cites W2043068531 @default.
- W2014320851 cites W2046258570 @default.
- W2014320851 cites W2047505600 @default.
- W2014320851 cites W2049528988 @default.
- W2014320851 cites W2049620839 @default.
- W2014320851 cites W2050484432 @default.
- W2014320851 cites W2050580817 @default.
- W2014320851 cites W2051236814 @default.
- W2014320851 cites W2052969855 @default.
- W2014320851 cites W2053517795 @default.
- W2014320851 cites W2055682170 @default.
- W2014320851 cites W2061348377 @default.
- W2014320851 cites W2061371060 @default.
- W2014320851 cites W2063020326 @default.
- W2014320851 cites W2064100897 @default.
- W2014320851 cites W2065443731 @default.
- W2014320851 cites W2066434636 @default.
- W2014320851 cites W2066880035 @default.
- W2014320851 cites W2068627420 @default.
- W2014320851 cites W2072649524 @default.
- W2014320851 cites W2073114083 @default.
- W2014320851 cites W2074906159 @default.
- W2014320851 cites W2075057594 @default.
- W2014320851 cites W2076513790 @default.
- W2014320851 cites W2076733156 @default.
- W2014320851 cites W2079293612 @default.
- W2014320851 cites W2080420512 @default.
- W2014320851 cites W2081911574 @default.
- W2014320851 cites W2083756305 @default.
- W2014320851 cites W2085468284 @default.
- W2014320851 cites W2087005871 @default.
- W2014320851 cites W2090262871 @default.
- W2014320851 cites W2091614744 @default.
- W2014320851 cites W2091911196 @default.
- W2014320851 cites W2095754960 @default.
- W2014320851 cites W2098796895 @default.