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• W2014346648 abstract "Isovolumic relaxation time (IVRT) and rapid filling time (RFT) were used to evaluate elasticity and compliance in 11 control subjects (Group 1), in nine patients with angina (Group 2), in 11 with hypertensive heart disease (Group 3), and in ten patients with healed myocardial infarction (Group 4). Pre-ejection period (PEP), pre-ejection period index (PEPI), left ventricular ejection time (LVET), left ventricular ejection time index (LVETI) and PEP/LVET ratio were all derived from simultaneous recordings of phonocardiograms, ECGs, apexcardiograms, and external carotid arterial pulses. No patients were in congestive heart failure and none were receiving medication. LVET and LVETI were the same in the control patient groups; PEP was slightly increased in patients with healed myocardial infarctions (p<0.05); and PEPI was prolonged in the patients with angina (p = 0.001). The PEP/LVET ratio too was different from the control group in patients with angina and hypertension (Groups 2 and 3 – p<0.02 and <0.05 respectively). The diastolic time intervals were significantly altered in that the IVRT was prolonged in angina patients (113.4 ± 28.3 msec), compared to control patients (85.7 ± 18.4 msec). It was found that in 6 out of 9 patients with angina, this interval exceeded the highest normal value (108 msec), hut that in only one out of 11 patients with HCVD and in three out of ten with healed infarctions, was this interval prolonged. RFT was increased in HCVD (113.8 ± 18.8 msec) and in healed myocardial infarction (123.8 ± 30.0 msec) patients, compared to the control group (94.5 ± 12.8 msec). Diastolic time intervals reflecting disorders in elasticity and compliance may occur in conjunction with alterations in systolic time intervals. Isovolumic relaxation time (IVRT) and rapid filling time (RFT) were used to evaluate elasticity and compliance in 11 control subjects (Group 1), in nine patients with angina (Group 2), in 11 with hypertensive heart disease (Group 3), and in ten patients with healed myocardial infarction (Group 4). Pre-ejection period (PEP), pre-ejection period index (PEPI), left ventricular ejection time (LVET), left ventricular ejection time index (LVETI) and PEP/LVET ratio were all derived from simultaneous recordings of phonocardiograms, ECGs, apexcardiograms, and external carotid arterial pulses. No patients were in congestive heart failure and none were receiving medication. LVET and LVETI were the same in the control patient groups; PEP was slightly increased in patients with healed myocardial infarctions (p<0.05); and PEPI was prolonged in the patients with angina (p = 0.001). The PEP/LVET ratio too was different from the control group in patients with angina and hypertension (Groups 2 and 3 – p<0.02 and <0.05 respectively). The diastolic time intervals were significantly altered in that the IVRT was prolonged in angina patients (113.4 ± 28.3 msec), compared to control patients (85.7 ± 18.4 msec). It was found that in 6 out of 9 patients with angina, this interval exceeded the highest normal value (108 msec), hut that in only one out of 11 patients with HCVD and in three out of ten with healed infarctions, was this interval prolonged. RFT was increased in HCVD (113.8 ± 18.8 msec) and in healed myocardial infarction (123.8 ± 30.0 msec) patients, compared to the control group (94.5 ± 12.8 msec). Diastolic time intervals reflecting disorders in elasticity and compliance may occur in conjunction with alterations in systolic time intervals." @default.
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• W2014346648 date "1975-07-01" @default.
• W2014346648 modified "2023-09-27" @default.
• W2014346648 title "Diastolic Time Intervals in Ischemic and Hypertensive Heart Disease" @default.
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• W2014346648 doi "https://doi.org/10.1378/chest.68.1.56" @default.
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