FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014354522> ?p ?o ?g. }

• W2014354522 endingPage "369" @default.
• W2014354522 startingPage "365" @default.
• W2014354522 abstract "To further explore the role of Sp1 and Sp3 in the estrogen regulated TFF1 gene transcription, chromatin immunoprecipitation (ChIP) assay was used to determine the association of estrogen receptor α (ERα), Sp1 and Sp3 with the endogenous trefoil factor 1 (TFF1) gene promoter in MCF-7 breast cancer cells. ERα and serine 5 phosphorylated RNA polymerase II, the form of RNA polymerase II associated with transcription initiation, were recruited to the TFF1 gene promoter following estrogen addition to MCF-7 cells cultured under estrogen deplete conditions. Both Sp1 and Sp3 were bound to the TFF1 gene promoter before and after estrogen treatment. Using the re-ChIP assay, we demonstrate that either Sp1 or Sp3 but not both bind to a TFF1 promoter. The co-occupancy of ERα and Sp1 on TFF1 promoter remains at similar level with and without estrogen, while that of ERα and Sp3 increased in the presence of estrogen. Further, we observed increased co-occupancy of Sp3 and serine 5 phosphorylated RNA polymerase II on the TFF1 promoter after estrogen treatment of cells. Taken together, these results provide evidence that Sp3 and ERα are involved in the estrogen induced transcription of the TFF1 gene. J. Cell. Biochem. 105: 365–369, 2008. © 2008 Wiley-Liss, Inc." @default.
• W2014354522 created "2016-06-24" @default.
• W2014354522 creator A5048849645 @default.
• W2014354522 creator A5058965019 @default.
• W2014354522 date "2008-10-01" @default.
• W2014354522 modified "2023-10-16" @default.
• W2014354522 title "Association of Sp3 and estrogen receptor α with the transcriptionally active trefoil factor 1 promoter in MCF-7 breast cancer cells" @default.
• W2014354522 cites W1974629239 @default.
• W2014354522 cites W1990189563 @default.
• W2014354522 cites W1996272511 @default.
• W2014354522 cites W1998441650 @default.
• W2014354522 cites W2008086014 @default.
• W2014354522 cites W2028075225 @default.
• W2014354522 cites W2038208040 @default.
• W2014354522 cites W2039576757 @default.
• W2014354522 cites W2041159570 @default.
• W2014354522 cites W2046137645 @default.
• W2014354522 cites W2047749014 @default.
• W2014354522 cites W2062056287 @default.
• W2014354522 cites W2104867660 @default.
• W2014354522 cites W2112907191 @default.
• W2014354522 cites W2124588434 @default.
• W2014354522 cites W2162623019 @default.
• W2014354522 cites W2165621847 @default.
• W2014354522 cites W2172088918 @default.
• W2014354522 doi "https://doi.org/10.1002/jcb.21832" @default.
• W2014354522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18543253" @default.
• W2014354522 hasPublicationYear "2008" @default.
• W2014354522 type Work @default.
• W2014354522 sameAs 2014354522 @default.
• W2014354522 citedByCount "11" @default.
• W2014354522 countsByYear W20143545222012 @default.
• W2014354522 countsByYear W20143545222013 @default.
• W2014354522 countsByYear W20143545222014 @default.
• W2014354522 countsByYear W20143545222015 @default.
• W2014354522 countsByYear W20143545222016 @default.
• W2014354522 countsByYear W20143545222017 @default.
• W2014354522 crossrefType "journal-article" @default.
• W2014354522 hasAuthorship W2014354522A5048849645 @default.
• W2014354522 hasAuthorship W2014354522A5058965019 @default.
• W2014354522 hasConcept C101762097 @default.
• W2014354522 hasConcept C104317684 @default.
• W2014354522 hasConcept C121608353 @default.
• W2014354522 hasConcept C134018914 @default.
• W2014354522 hasConcept C134320426 @default.
• W2014354522 hasConcept C150194340 @default.
• W2014354522 hasConcept C153911025 @default.
• W2014354522 hasConcept C172313692 @default.
• W2014354522 hasConcept C185592680 @default.
• W2014354522 hasConcept C2777164284 @default.
• W2014354522 hasConcept C502942594 @default.
• W2014354522 hasConcept C530470458 @default.
• W2014354522 hasConcept C54355233 @default.
• W2014354522 hasConcept C55493867 @default.
• W2014354522 hasConcept C57467964 @default.
• W2014354522 hasConcept C64350747 @default.
• W2014354522 hasConcept C84606932 @default.
• W2014354522 hasConcept C86339819 @default.
• W2014354522 hasConcept C86803240 @default.
• W2014354522 hasConcept C96307122 @default.
• W2014354522 hasConceptScore W2014354522C101762097 @default.
• W2014354522 hasConceptScore W2014354522C104317684 @default.
• W2014354522 hasConceptScore W2014354522C121608353 @default.
• W2014354522 hasConceptScore W2014354522C134018914 @default.
• W2014354522 hasConceptScore W2014354522C134320426 @default.
• W2014354522 hasConceptScore W2014354522C150194340 @default.
• W2014354522 hasConceptScore W2014354522C153911025 @default.
• W2014354522 hasConceptScore W2014354522C172313692 @default.
• W2014354522 hasConceptScore W2014354522C185592680 @default.
• W2014354522 hasConceptScore W2014354522C2777164284 @default.
• W2014354522 hasConceptScore W2014354522C502942594 @default.
• W2014354522 hasConceptScore W2014354522C530470458 @default.
• W2014354522 hasConceptScore W2014354522C54355233 @default.
• W2014354522 hasConceptScore W2014354522C55493867 @default.
• W2014354522 hasConceptScore W2014354522C57467964 @default.
• W2014354522 hasConceptScore W2014354522C64350747 @default.
• W2014354522 hasConceptScore W2014354522C84606932 @default.
• W2014354522 hasConceptScore W2014354522C86339819 @default.
• W2014354522 hasConceptScore W2014354522C86803240 @default.
• W2014354522 hasConceptScore W2014354522C96307122 @default.
• W2014354522 hasIssue "2" @default.
• W2014354522 hasLocation W20143545221 @default.
• W2014354522 hasOpenAccess W2014354522 @default.
• W2014354522 hasPrimaryLocation W20143545221 @default.
• W2014354522 hasRelatedWork W1970185134 @default.
• W2014354522 hasRelatedWork W1985682532 @default.
• W2014354522 hasRelatedWork W1998415342 @default.
• W2014354522 hasRelatedWork W2009125857 @default.
• W2014354522 hasRelatedWork W2014354522 @default.
• W2014354522 hasRelatedWork W2019884543 @default.
• W2014354522 hasRelatedWork W2029821696 @default.
• W2014354522 hasRelatedWork W2114410603 @default.
• W2014354522 hasRelatedWork W2132168822 @default.
• W2014354522 hasRelatedWork W2940963403 @default.
• W2014354522 hasVolume "105" @default.
• W2014354522 isParatext "false" @default.
• W2014354522 isRetracted "false" @default.
• W2014354522 magId "2014354522" @default.

• next