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- W2014358009 abstract "New syntheses of densely functionalized protected derivatives of 3-amino-3,6-dideoxyaminosugars have been accomplished in an efficient and straightforward manner. The key step of such approaches involves a highly stereoselective titanium-mediated aldol addition of a chiral α-bromo ketone, easily available from lactate esters, to crotonaldehyde. Further functional group transformations, including a new regioselective Staudinger–aza-Wittig reaction of an azidodiacetate, afford in a few steps and high yield the desired carbohydrates as advanced intermediates capable of participating in subsequent glycosylation reactions." @default.
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- W2014358009 date "2012-01-01" @default.
- W2014358009 modified "2023-10-11" @default.
- W2014358009 title "Stereoselective synthesis of protected 3-amino-3,6-dideoxyaminosugars" @default.
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- W2014358009 doi "https://doi.org/10.1039/c2ob25793a" @default.
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