Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014359107> ?p ?o ?g. }
- W2014359107 endingPage "471" @default.
- W2014359107 startingPage "456" @default.
- W2014359107 abstract "Natural selection imposed by pathogens is a strong and pervasive evolutionary force structuring genetic diversity within their hosts’ genomes and populations. As a model system for understanding the genomic impact of host–parasite coevolution, we have been studying the evolutionary dynamics of disease resistance genes in wild relatives of the cultivated tomato species. In this study, we investigated the sequence variation and evolutionary history of three linked genes involved in pathogen resistance in populations of Solanum peruvianum (Pto, Fen, and Prf). These genes encode proteins, which form a multimeric complex and together activate defense responses. We used standard linkage disequilibrium, as well as partitioning of linkage disequilibrium components across populations and correlated substitution analysis to identify amino acid positions that are candidates for coevolving sites between Pto/Fen and Prf. These candidates were mapped onto known and predicted structures of Pto, Fen and Prf to visualize putative coevolving regions between proteins. We discuss the functional significance of these coevolving pairs in the context of what is known from previous structure–function studies of Pto, Fen and Prf." @default.
- W2014359107 created "2016-06-24" @default.
- W2014359107 creator A5042641479 @default.
- W2014359107 creator A5051798099 @default.
- W2014359107 creator A5062512980 @default.
- W2014359107 date "2014-10-01" @default.
- W2014359107 modified "2023-10-06" @default.
- W2014359107 title "Epistatic selection and coadaptation in the Prf resistance complex of wild tomato" @default.
- W2014359107 cites W1637216700 @default.
- W2014359107 cites W1822446915 @default.
- W2014359107 cites W1968295940 @default.
- W2014359107 cites W1972857786 @default.
- W2014359107 cites W1973298000 @default.
- W2014359107 cites W1973442316 @default.
- W2014359107 cites W1973891844 @default.
- W2014359107 cites W1982057360 @default.
- W2014359107 cites W1983141259 @default.
- W2014359107 cites W1984017573 @default.
- W2014359107 cites W1985912235 @default.
- W2014359107 cites W1990074132 @default.
- W2014359107 cites W2001583270 @default.
- W2014359107 cites W2003647281 @default.
- W2014359107 cites W2019100295 @default.
- W2014359107 cites W2024784465 @default.
- W2014359107 cites W2028254759 @default.
- W2014359107 cites W2029702026 @default.
- W2014359107 cites W2037362828 @default.
- W2014359107 cites W2039928366 @default.
- W2014359107 cites W2050455405 @default.
- W2014359107 cites W2057332617 @default.
- W2014359107 cites W2060247350 @default.
- W2014359107 cites W2060410804 @default.
- W2014359107 cites W2064301248 @default.
- W2014359107 cites W2070272438 @default.
- W2014359107 cites W2074651227 @default.
- W2014359107 cites W2086261779 @default.
- W2014359107 cites W2086557093 @default.
- W2014359107 cites W2087300028 @default.
- W2014359107 cites W2092948130 @default.
- W2014359107 cites W2098440710 @default.
- W2014359107 cites W2100075411 @default.
- W2014359107 cites W2104459579 @default.
- W2014359107 cites W2112799266 @default.
- W2014359107 cites W2115292592 @default.
- W2014359107 cites W2116776415 @default.
- W2014359107 cites W2119325866 @default.
- W2014359107 cites W2119759963 @default.
- W2014359107 cites W2120501631 @default.
- W2014359107 cites W2121046514 @default.
- W2014359107 cites W2125721380 @default.
- W2014359107 cites W2127416600 @default.
- W2014359107 cites W2128573945 @default.
- W2014359107 cites W2133475209 @default.
- W2014359107 cites W2134030532 @default.
- W2014359107 cites W2135353885 @default.
- W2014359107 cites W2136193576 @default.
- W2014359107 cites W2140784970 @default.
- W2014359107 cites W2142417092 @default.
- W2014359107 cites W2151061572 @default.
- W2014359107 cites W2153149273 @default.
- W2014359107 cites W2154097633 @default.
- W2014359107 cites W2154845780 @default.
- W2014359107 cites W2155201844 @default.
- W2014359107 cites W2161496396 @default.
- W2014359107 cites W2162157671 @default.
- W2014359107 cites W2165209158 @default.
- W2014359107 cites W2304461458 @default.
- W2014359107 cites W4295216797 @default.
- W2014359107 doi "https://doi.org/10.1016/j.meegid.2014.06.019" @default.
- W2014359107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24997333" @default.
- W2014359107 hasPublicationYear "2014" @default.
- W2014359107 type Work @default.
- W2014359107 sameAs 2014359107 @default.
- W2014359107 citedByCount "5" @default.
- W2014359107 countsByYear W20143591072014 @default.
- W2014359107 countsByYear W20143591072018 @default.
- W2014359107 countsByYear W20143591072020 @default.
- W2014359107 countsByYear W20143591072022 @default.
- W2014359107 crossrefType "journal-article" @default.
- W2014359107 hasAuthorship W2014359107A5042641479 @default.
- W2014359107 hasAuthorship W2014359107A5051798099 @default.
- W2014359107 hasAuthorship W2014359107A5062512980 @default.
- W2014359107 hasBestOaLocation W20143591072 @default.
- W2014359107 hasConcept C104317684 @default.
- W2014359107 hasConcept C141231307 @default.
- W2014359107 hasConcept C151730666 @default.
- W2014359107 hasConcept C154945302 @default.
- W2014359107 hasConcept C180754005 @default.
- W2014359107 hasConcept C197754878 @default.
- W2014359107 hasConcept C2779343474 @default.
- W2014359107 hasConcept C33009525 @default.
- W2014359107 hasConcept C35605836 @default.
- W2014359107 hasConcept C41008148 @default.
- W2014359107 hasConcept C49735019 @default.
- W2014359107 hasConcept C54355233 @default.
- W2014359107 hasConcept C61727976 @default.
- W2014359107 hasConcept C68873052 @default.
- W2014359107 hasConcept C75268714 @default.