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- W2014359369 abstract "Insulin release in response to glucose was measured after culture of islets from ob/ob-mice in a Ca2+-deficient medium. The stimulatory effect of 20 mM glucose disappeared after addition of 1 μM L-epinephrine, and it was reversed into inhibition when the medium contained 0.1 to 10 μM clonidine. Glucose inhibited insulin release also after activation of the α2-adrenoceptors with B-HT 933, whereas blocking of these receptors with idazoxan removed glucose inhibition in the presence of clonidine. It is concluded that α2-adrenergic activation provides an efficient means of unmasking the inhibitory component in the action of glucose on insulin release." @default.
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- W2014359369 title "Unmasking of the inhibitory action of glucose on insulin release after α2-adrenergic activation" @default.
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- W2014359369 doi "https://doi.org/10.1016/s0006-291x(86)80027-4" @default.
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