FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014362456> ?p ?o ?g. }

• W2014362456 endingPage "673" @default.
• W2014362456 startingPage "657" @default.
• W2014362456 abstract "Genetically modified mice represent useful tools for traumatic brain injury (TBI) research and attractive preclinical models for the development of novel therapeutics. Experimental methods that minimize the number of mice needed may increase the pace of discovery. With this in mind, we developed and characterized a prototype electromagnetic (EM) controlled cortical impact device along with refined surgical and behavioral testing techniques. By varying the depth of impact between 1.0 and 3.0 mm, we found that the EM device was capable of producing a broad range of injury severities. Histologically, 2.0-mm impact depth injuries produced by the EM device were similar to 1.0-mm impact depth injuries produced by a commercially available pneumatic device. Behaviorally, 2.0-, 2.5-, and 3.0-mm impacts impaired hidden platform and probe trial water maze performance, whereas 1.5-mm impacts did not. Rotorod and visible platform water maze deficits were also found following 2.5- and 3.0-mm impacts. No impairment of conditioned fear performance was detected. No differences were found between sexes of mice. Inter-operator reliability was very good. Behaviorally, we found that we could statistically distinguish between injury depths differing by 0.5 mm using 12 mice per group and between injury depths differing by 1.0 mm with 7–8 mice per group. Thus, the EM impactor and refined surgical and behavioral testing techniques may offer a reliable and convenient framework for preclinical TBI research involving mice." @default.
• W2014362456 created "2016-06-24" @default.
• W2014362456 creator A5013434125 @default.
• W2014362456 creator A5025683337 @default.
• W2014362456 creator A5033699423 @default.
• W2014362456 creator A5045394358 @default.
• W2014362456 creator A5048026511 @default.
• W2014362456 creator A5054061784 @default.
• W2014362456 creator A5057957903 @default.
• W2014362456 creator A5065549626 @default.
• W2014362456 creator A5081494138 @default.
• W2014362456 creator A5088998527 @default.
• W2014362456 date "2007-04-01" @default.
• W2014362456 modified "2023-10-14" @default.
• W2014362456 title "Electromagnetic Controlled Cortical Impact Device for Precise, Graded Experimental Traumatic Brain Injury" @default.
• W2014362456 cites W1483724290 @default.
• W2014362456 cites W1629602451 @default.
• W2014362456 cites W1966776682 @default.
• W2014362456 cites W1968594432 @default.
• W2014362456 cites W1973633053 @default.
• W2014362456 cites W1975241767 @default.
• W2014362456 cites W1984870586 @default.
• W2014362456 cites W1989282675 @default.
• W2014362456 cites W1992480976 @default.
• W2014362456 cites W1998406619 @default.
• W2014362456 cites W1999934730 @default.
• W2014362456 cites W2000688919 @default.
• W2014362456 cites W2003603360 @default.
• W2014362456 cites W2011850678 @default.
• W2014362456 cites W2011885704 @default.
• W2014362456 cites W2015122191 @default.
• W2014362456 cites W2016108891 @default.
• W2014362456 cites W2016723726 @default.
• W2014362456 cites W2017132655 @default.
• W2014362456 cites W2018465654 @default.
• W2014362456 cites W2020408289 @default.
• W2014362456 cites W2020773902 @default.
• W2014362456 cites W2026311918 @default.
• W2014362456 cites W2028535633 @default.
• W2014362456 cites W2029707852 @default.
• W2014362456 cites W2031244297 @default.
• W2014362456 cites W2033665331 @default.
• W2014362456 cites W2034679108 @default.
• W2014362456 cites W2043704650 @default.
• W2014362456 cites W2045663952 @default.
• W2014362456 cites W2050607339 @default.
• W2014362456 cites W2066865589 @default.
• W2014362456 cites W2067629356 @default.
• W2014362456 cites W2071621853 @default.
• W2014362456 cites W2072122929 @default.
• W2014362456 cites W2077812845 @default.
• W2014362456 cites W2079730704 @default.
• W2014362456 cites W2081122171 @default.
• W2014362456 cites W2081207317 @default.
• W2014362456 cites W2081957132 @default.
• W2014362456 cites W2084523293 @default.
• W2014362456 cites W2086070682 @default.
• W2014362456 cites W2089885268 @default.
• W2014362456 cites W2094545732 @default.
• W2014362456 cites W2111967645 @default.
• W2014362456 cites W2115390080 @default.
• W2014362456 cites W2119556701 @default.
• W2014362456 cites W2126800086 @default.
• W2014362456 cites W2136277561 @default.
• W2014362456 cites W2143304035 @default.
• W2014362456 cites W2153945143 @default.
• W2014362456 cites W2158713023 @default.
• W2014362456 doi "https://doi.org/10.1089/neu.2006.0011" @default.
• W2014362456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2435168" @default.
• W2014362456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17439349" @default.
• W2014362456 hasPublicationYear "2007" @default.
• W2014362456 type Work @default.
• W2014362456 sameAs 2014362456 @default.
• W2014362456 citedByCount "179" @default.
• W2014362456 countsByYear W20143624562012 @default.
• W2014362456 countsByYear W20143624562013 @default.
• W2014362456 countsByYear W20143624562014 @default.
• W2014362456 countsByYear W20143624562015 @default.
• W2014362456 countsByYear W20143624562016 @default.
• W2014362456 countsByYear W20143624562017 @default.
• W2014362456 countsByYear W20143624562018 @default.
• W2014362456 countsByYear W20143624562019 @default.
• W2014362456 countsByYear W20143624562020 @default.
• W2014362456 countsByYear W20143624562021 @default.
• W2014362456 countsByYear W20143624562022 @default.
• W2014362456 countsByYear W20143624562023 @default.
• W2014362456 crossrefType "journal-article" @default.
• W2014362456 hasAuthorship W2014362456A5013434125 @default.
• W2014362456 hasAuthorship W2014362456A5025683337 @default.
• W2014362456 hasAuthorship W2014362456A5033699423 @default.
• W2014362456 hasAuthorship W2014362456A5045394358 @default.
• W2014362456 hasAuthorship W2014362456A5048026511 @default.
• W2014362456 hasAuthorship W2014362456A5054061784 @default.
• W2014362456 hasAuthorship W2014362456A5057957903 @default.
• W2014362456 hasAuthorship W2014362456A5065549626 @default.
• W2014362456 hasAuthorship W2014362456A5081494138 @default.
• W2014362456 hasAuthorship W2014362456A5088998527 @default.
• W2014362456 hasBestOaLocation W20143624562 @default.

• next