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• W2014363487 abstract "To study the effect of zonisamide on experimental tremors in rats.Effect of zonisamide on harmaline- or oxotreorine-induced tremors, and tacrine-induced tremulous jaw movements (TJMs) was studied.Zonisamide significantly suppressed both harmaline- and oxotremorine-induced tremors dose-dependently. Zonisamide also significantly suppressed tacrine-induced TJMs, and this effect was not lost under conditions of monoamine-depletion or dopaminergic blockade.The anti-tremor effects of zonisamide may be achieved by a non-dopaminergic mechanism. Since it effectively suppressed tremors that are based on different kinds of tremors, we propose a novel perspective of clinical potential of zonisamide as a non-specific, anti-tremor drug." @default.
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• W2014363487 date "2008-01-01" @default.
• W2014363487 modified "2023-10-01" @default.
• W2014363487 title "Effects of zonisamide on experimental tremors in rats" @default.
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• W2014363487 doi "https://doi.org/10.1016/j.parkreldis.2007.05.008" @default.
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