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- W2014365029 abstract "Abstract Besides its effects of the genetic material and function, chromate also immediately affects the structure and function of cell membranes. With human erythrocytes, chromate produces alterations in cell size and shape, it impairs the anion transport function, and it causes modifications in membrane constituents. The proteins have been analysed by one‐ and two‐dimensional gel electrophoresis and by fast protein liquid chromatography (FPLC). The main chromate effects are the crosslinking of proteins including the membrane protein bands 1 and 2 (spectrin) and haemoglobin. Furthermore, a 40.000 D membrane protein fraction is modified. Chromate may react directly with membrane constituents but evidence also points to the formation of reactive oxygen compounds which in turn may react with proteins and lipids of the cell membrane." @default.
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- W2014365029 date "1989-05-15" @default.
- W2014365029 modified "2023-09-23" @default.
- W2014365029 title "Electrophoretic and liquid chromatographic characterization of red cell membrane proteins modified by chromate" @default.
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- W2014365029 doi "https://doi.org/10.1080/02772248909357422" @default.
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