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- W2014370080 abstract "A partially purified lipase produced by Staphylococcus aureaus is inhibited by tetracycline. This effect is exhibited when 3.3 × 10-3 M tetracycline is added to the enzyme at a concentration of 0.6 mg/ml. The inactivation of the enzyme by tetracycline was complete after 10 min of incubation at 37° C. Increasing the preincubation period up to 24 hours did not increase the degree of inactivation. Divalent ions, such as Ca++, Mg++, and Mn++ did not effect the action of the drug on the enzyme. Inactivation by tetracycline was dependent on the amount of protein in the reaction mixture. The addition of 5 mg of bovine serum albumin (BSA) to the mixture completely neutralized the inhibitory effect." @default.
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- W2014370080 date "1973-03-01" @default.
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- W2014370080 title "Inhibition of Staphylococcus Aureus Lipase by Tetracycline" @default.
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- W2014370080 doi "https://doi.org/10.1111/1523-1747.ep12682065" @default.
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