FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014370576> ?p ?o ?g. }

• W2014370576 endingPage "4137" @default.
• W2014370576 startingPage "4127" @default.
• W2014370576 abstract "Abstract The nuclear receptor corepressor RIP140 is essential in the ovary for ovulation, but is not required for follicle growth and luteinization. To identify genes that may be subject to regulation by RIP140 or play a role in ovulation, we compared ovarian gene expression profiles in untreated immature wild-type and RIP140 null mice and after treatment with pregnant mare serum gonadotropin and human chorionic gonadotropin. Many genes involved in signaling, extracellular matrix formation, cell-cell attachment, and adhesion were aberrantly regulated in the absence of RIP140, varying according to the hormone status of the mice. Notable among these was the reduced expression of a number of genes that encode components of signaling pathways and matrix proteins required for cumulus expansion, a key remodeling process necessary for ovulation. Histological analysis confirmed that cumulus expansion in RIP140 null mice is reduced, oocyte detachment from the mural cell wall is impaired, and follicles fail to rupture in response to LH. Although the expression of many genes involved in cumulus cell expansion was reduced, there was a subset of genes involved in extracellular matrix formation and cell-cell interactions that was up-regulated and may interfere with ovarian tissue remodeling. We propose that widespread gene dysregulation in ovarian tissues in the absence of RIP140 leads to the anovulatory phenotype. This helps to define an important role for RIP140 in the regulation of multiple processes leading to ovulation." @default.
• W2014370576 created "2016-06-24" @default.
• W2014370576 creator A5019231390 @default.
• W2014370576 creator A5033033065 @default.
• W2014370576 creator A5056480658 @default.
• W2014370576 creator A5074670704 @default.
• W2014370576 creator A5081698567 @default.
• W2014370576 creator A5083722213 @default.
• W2014370576 date "2005-09-01" @default.
• W2014370576 modified "2023-10-17" @default.
• W2014370576 title "Multiple Signaling Defects in the Absence of RIP140 Impair Both Cumulus Expansion and Follicle Rupture" @default.
• W2014370576 cites W1551142193 @default.
• W2014370576 cites W1602722523 @default.
• W2014370576 cites W1751242022 @default.
• W2014370576 cites W1823777871 @default.
• W2014370576 cites W1893337122 @default.
• W2014370576 cites W1968234426 @default.
• W2014370576 cites W1969968324 @default.
• W2014370576 cites W1970118949 @default.
• W2014370576 cites W1970616802 @default.
• W2014370576 cites W1974738966 @default.
• W2014370576 cites W1981231686 @default.
• W2014370576 cites W1995586478 @default.
• W2014370576 cites W1997955344 @default.
• W2014370576 cites W2008015660 @default.
• W2014370576 cites W2013232618 @default.
• W2014370576 cites W2022773997 @default.
• W2014370576 cites W2034877305 @default.
• W2014370576 cites W2039395012 @default.
• W2014370576 cites W2039532690 @default.
• W2014370576 cites W2042581098 @default.
• W2014370576 cites W2047083811 @default.
• W2014370576 cites W2048466881 @default.
• W2014370576 cites W2058374230 @default.
• W2014370576 cites W2059547297 @default.
• W2014370576 cites W2063017336 @default.
• W2014370576 cites W2068505754 @default.
• W2014370576 cites W2084172300 @default.
• W2014370576 cites W2084722787 @default.
• W2014370576 cites W2085052924 @default.
• W2014370576 cites W2085195448 @default.
• W2014370576 cites W2087236819 @default.
• W2014370576 cites W2088472987 @default.
• W2014370576 cites W2092242553 @default.
• W2014370576 cites W2092755638 @default.
• W2014370576 cites W2100729936 @default.
• W2014370576 cites W2112760662 @default.
• W2014370576 cites W2115410748 @default.
• W2014370576 cites W2116591857 @default.
• W2014370576 cites W2116761578 @default.
• W2014370576 cites W2117284870 @default.
• W2014370576 cites W2117376104 @default.
• W2014370576 cites W2118376852 @default.
• W2014370576 cites W2127318722 @default.
• W2014370576 cites W2129261094 @default.
• W2014370576 cites W2148022618 @default.
• W2014370576 cites W2148720103 @default.
• W2014370576 cites W2150926065 @default.
• W2014370576 cites W2156720376 @default.
• W2014370576 cites W2158312683 @default.
• W2014370576 cites W2158404726 @default.
• W2014370576 cites W2159731164 @default.
• W2014370576 cites W4245667286 @default.
• W2014370576 cites W4245809956 @default.
• W2014370576 cites W4255522723 @default.
• W2014370576 cites W61622498 @default.
• W2014370576 doi "https://doi.org/10.1210/en.2005-0348" @default.
• W2014370576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15919748" @default.
• W2014370576 hasPublicationYear "2005" @default.
• W2014370576 type Work @default.
• W2014370576 sameAs 2014370576 @default.
• W2014370576 citedByCount "36" @default.
• W2014370576 countsByYear W20143705762013 @default.
• W2014370576 countsByYear W20143705762014 @default.
• W2014370576 countsByYear W20143705762015 @default.
• W2014370576 countsByYear W20143705762017 @default.
• W2014370576 countsByYear W20143705762018 @default.
• W2014370576 countsByYear W20143705762020 @default.
• W2014370576 crossrefType "journal-article" @default.
• W2014370576 hasAuthorship W2014370576A5019231390 @default.
• W2014370576 hasAuthorship W2014370576A5033033065 @default.
• W2014370576 hasAuthorship W2014370576A5056480658 @default.
• W2014370576 hasAuthorship W2014370576A5074670704 @default.
• W2014370576 hasAuthorship W2014370576A5081698567 @default.
• W2014370576 hasAuthorship W2014370576A5083722213 @default.
• W2014370576 hasBestOaLocation W20143705761 @default.
• W2014370576 hasConcept C126322002 @default.
• W2014370576 hasConcept C134018914 @default.
• W2014370576 hasConcept C189165786 @default.
• W2014370576 hasConcept C196843134 @default.
• W2014370576 hasConcept C2776690073 @default.
• W2014370576 hasConcept C2777702977 @default.
• W2014370576 hasConcept C2778324911 @default.
• W2014370576 hasConcept C2780536345 @default.
• W2014370576 hasConcept C71315377 @default.
• W2014370576 hasConcept C71924100 @default.
• W2014370576 hasConcept C86803240 @default.
• W2014370576 hasConcept C95444343 @default.

• next