FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014371939> ?p ?o ?g. }

• W2014371939 endingPage "2542" @default.
• W2014371939 startingPage "2536" @default.
• W2014371939 abstract "Hypertrophic cardiomyopathy (HCM) often causes sudden, unexpected death in adolescents and young adults. Alterations in myocardial metabolism are considered to be causes for contractile dysfunction. We examined the question of whether metabolic abnormalities antedate the manifestation of symptoms in patients with HCM.Proton-decoupled 31P NMR spectroscopy of the anterior left ventricular wall of the heart of 14 young, asymptomatic patients with HCM was performed with a 1.5-T whole-body imager. Spectra of the phosphate metabolites were compared with those of normal control subjects. The patients exhibited a significantly reduced (P<0.02) ratio of phosphocreatine (PCr) to ATP of 1.98+/-0.37 (mean+/-SD), compared with 2.46+/-0.53 obtained in 11 normal control subjects. In addition, the group of patients with severe hypertrophy of the interventricular septum (n=8) showed a significantly increased (P<0.05) Pi-to-PCr ratio, with a Pi x 100/PCr of 20.0+/-8.3 versus 9.7+/-7.2 in control subjects. Both abnormalities are similar to those found in ischemic myocardium. This view is also supported by a significantly increased (P<0.01) phosphomonoester (PME)-to-PCr ratio, with a PME x 100/PCr of 20.7+/-11.2 compared with 8.4+/-6.7 in control subjects, indicating altered glucose metabolism.31P NMR spectroscopy detects alterations of myocardial metabolism in asymptomatic patients with HCM. These alterations may contribute to the understanding of the pathophysiology and natural history of the disease." @default.
• W2014371939 created "2016-06-24" @default.
• W2014371939 creator A5003979485 @default.
• W2014371939 creator A5016874284 @default.
• W2014371939 creator A5025429338 @default.
• W2014371939 creator A5027762460 @default.
• W2014371939 creator A5035031798 @default.
• W2014371939 creator A5035581752 @default.
• W2014371939 creator A5056737315 @default.
• W2014371939 creator A5059986197 @default.
• W2014371939 creator A5067486645 @default.
• W2014371939 creator A5072819373 @default.
• W2014371939 creator A5078267921 @default.
• W2014371939 date "1998-06-30" @default.
• W2014371939 modified "2023-10-16" @default.
• W2014371939 title "³¹ P NMR Spectroscopy Detects Metabolic Abnormalities in Asymptomatic Patients With Hypertrophic Cardiomyopathy" @default.
• W2014371939 cites W1969899562 @default.
• W2014371939 cites W1969990813 @default.
• W2014371939 cites W1970026909 @default.
• W2014371939 cites W1975792971 @default.
• W2014371939 cites W1985953072 @default.
• W2014371939 cites W1991559072 @default.
• W2014371939 cites W2004957860 @default.
• W2014371939 cites W2006501897 @default.
• W2014371939 cites W2013638474 @default.
• W2014371939 cites W2016996526 @default.
• W2014371939 cites W2018205629 @default.
• W2014371939 cites W2025532642 @default.
• W2014371939 cites W2030705954 @default.
• W2014371939 cites W2032852179 @default.
• W2014371939 cites W2042562951 @default.
• W2014371939 cites W2044943191 @default.
• W2014371939 cites W2052205471 @default.
• W2014371939 cites W2071222217 @default.
• W2014371939 cites W2074409624 @default.
• W2014371939 cites W2079496793 @default.
• W2014371939 cites W2081133653 @default.
• W2014371939 cites W2092570151 @default.
• W2014371939 cites W2098877347 @default.
• W2014371939 cites W2100650040 @default.
• W2014371939 cites W2129533522 @default.
• W2014371939 cites W2154325748 @default.
• W2014371939 cites W2235681635 @default.
• W2014371939 cites W2321389043 @default.
• W2014371939 cites W2894070997 @default.
• W2014371939 doi "https://doi.org/10.1161/01.cir.97.25.2536" @default.
• W2014371939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9657474" @default.
• W2014371939 hasPublicationYear "1998" @default.
• W2014371939 type Work @default.
• W2014371939 sameAs 2014371939 @default.
• W2014371939 citedByCount "174" @default.
• W2014371939 countsByYear W20143719392012 @default.
• W2014371939 countsByYear W20143719392013 @default.
• W2014371939 countsByYear W20143719392014 @default.
• W2014371939 countsByYear W20143719392015 @default.
• W2014371939 countsByYear W20143719392016 @default.
• W2014371939 countsByYear W20143719392017 @default.
• W2014371939 countsByYear W20143719392018 @default.
• W2014371939 countsByYear W20143719392019 @default.
• W2014371939 countsByYear W20143719392020 @default.
• W2014371939 countsByYear W20143719392021 @default.
• W2014371939 countsByYear W20143719392022 @default.
• W2014371939 countsByYear W20143719392023 @default.
• W2014371939 crossrefType "journal-article" @default.
• W2014371939 hasAuthorship W2014371939A5003979485 @default.
• W2014371939 hasAuthorship W2014371939A5016874284 @default.
• W2014371939 hasAuthorship W2014371939A5025429338 @default.
• W2014371939 hasAuthorship W2014371939A5027762460 @default.
• W2014371939 hasAuthorship W2014371939A5035031798 @default.
• W2014371939 hasAuthorship W2014371939A5035581752 @default.
• W2014371939 hasAuthorship W2014371939A5056737315 @default.
• W2014371939 hasAuthorship W2014371939A5059986197 @default.
• W2014371939 hasAuthorship W2014371939A5067486645 @default.
• W2014371939 hasAuthorship W2014371939A5072819373 @default.
• W2014371939 hasAuthorship W2014371939A5078267921 @default.
• W2014371939 hasBestOaLocation W20143719391 @default.
• W2014371939 hasConcept C10162356 @default.
• W2014371939 hasConcept C126322002 @default.
• W2014371939 hasConcept C134018914 @default.
• W2014371939 hasConcept C164705383 @default.
• W2014371939 hasConcept C167414201 @default.
• W2014371939 hasConcept C2777910003 @default.
• W2014371939 hasConcept C2778198053 @default.
• W2014371939 hasConcept C2778626300 @default.
• W2014371939 hasConcept C2778797674 @default.
• W2014371939 hasConcept C2778921608 @default.
• W2014371939 hasConcept C2779740085 @default.
• W2014371939 hasConcept C2780074459 @default.
• W2014371939 hasConcept C2780185194 @default.
• W2014371939 hasConcept C2986317502 @default.
• W2014371939 hasConcept C71924100 @default.
• W2014371939 hasConceptScore W2014371939C10162356 @default.
• W2014371939 hasConceptScore W2014371939C126322002 @default.
• W2014371939 hasConceptScore W2014371939C134018914 @default.
• W2014371939 hasConceptScore W2014371939C164705383 @default.
• W2014371939 hasConceptScore W2014371939C167414201 @default.
• W2014371939 hasConceptScore W2014371939C2777910003 @default.
• W2014371939 hasConceptScore W2014371939C2778198053 @default.

• next