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- W2014373502 abstract "Genome projects for eukaryotic organisms were launched with the aim of determining the complete nucleotide sequences of selected model species, including humans, yeast, nematodes and Arabidopsis. In a complementary, more functional approach, programmes were then started to identify the total set of expressed genes by sequencing mRNA-derived cDNAs, termed `expressed sequence tags' (ESTs). The EST approach has already proven its utility, rapidly generating lots of useful information at a relatively low cost; such projects have been initiated in different higher plant species, including Arabidopsis[ 1 Cooke R. et al. Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs. Plant J. 1996; 9: 101-124 Crossref PubMed Scopus (177) Google Scholar ]. However, attempts to ascribe functions to novel nucleotide sequences are often inconclusive and thus genetic approaches have to be used. Are there still plant-specific limitations to such approaches?" @default.
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- W2014373502 title "Physcomitrella and Arabidopsis: the David and Goliath of reverse genetics" @default.
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- W2014373502 doi "https://doi.org/10.1016/s1360-1385(98)01257-6" @default.
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