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- W2014379440 abstract "GC levels were assessed at 37 loci across 30 Mb of Xq26.1-qter, a region physically mopped in overlapping yeast artificial chromosome clones. In 8 Mb of R band Xq26, GC is relatively high (up to 44%) in the proximal 4 Mb and relatively low (40-41%) in the distal 4 Mb. Consistently low GC values (38-41%) are observed in G band Xq27. In contrast, further toward the telomere in Xq28, the GC level rises progressively to reach 52% at 2 to 4 Mb from the end of the chromosome; this region is delimited by low GC loci. Across these regions of Xq, the content of rare-cutter restriction enzyme sites containing CpG, including CpG islands in the most completely mapped Xq26-27.1 region, is correlated with GC level. Isochore mapping can thus provide one index of putative gene content across mapped regions." @default.
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- W2014379440 date "1993-08-01" @default.
- W2014379440 modified "2023-09-25" @default.
- W2014379440 title "Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter" @default.
- W2014379440 doi "https://doi.org/10.1006/geno.1993.1347" @default.
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