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• W2014395220 abstract "Dendritic cells (DCs), the sentinels of immunity, reside in almost every organ of the body. These cells are responsible for initiating immune responses against infectious agents. DCs are divided into different subsets based on their biological functions, with plasmacytoid DCs (pDCs) and conventional DCs (cDCs) being two major populations. The ability of DCs to protect against malaria infection was recently questioned when pDCs were reported to be a reservoir for rodent Plasmodium spp. in the spleen. This opinion article explores how the occupation of pDCs by the parasite may corrupt immunity against malaria. Dendritic cells (DCs), the sentinels of immunity, reside in almost every organ of the body. These cells are responsible for initiating immune responses against infectious agents. DCs are divided into different subsets based on their biological functions, with plasmacytoid DCs (pDCs) and conventional DCs (cDCs) being two major populations. The ability of DCs to protect against malaria infection was recently questioned when pDCs were reported to be a reservoir for rodent Plasmodium spp. in the spleen. This opinion article explores how the occupation of pDCs by the parasite may corrupt immunity against malaria." @default.
• W2014395220 created "2016-06-24" @default.
• W2014395220 creator A5031307625 @default.
• W2014395220 date "2012-05-01" @default.
• W2014395220 modified "2023-09-27" @default.
• W2014395220 title "Are plasmacytoid dendritic cells the misguided sentinels of malarial immunity?" @default.
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• W2014395220 doi "https://doi.org/10.1016/j.pt.2012.01.007" @default.
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