FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014403312> ?p ?o ?g. }

• W2014403312 endingPage "57" @default.
• W2014403312 startingPage "47" @default.
• W2014403312 abstract "Serum complement cascade, a part of innate immunity required for host protection against invading pathogens, is also a mediator of various forms of disease and injury. It is activated by classical, lectin, and alternative pathways that lead to activation of C3 component by C3 convertases, release of C3b opsonin, C5 conversion and eventually membrane attack complex formation. The tightly regulated activation process yields also C3a and C5a anaphylatoxins, which target a broad spectrum of immune and non-immune cells. The review discusses the involvement of the complement cascade in kidney disease pathogenesis and injury. The role of the complement pathways in autoantibody-mediated forms of glomerulonephritis (lupus nephritis, anti-glomerular basement membrane disease, anti-neutrophil cytoplasmic autoantibody-induced or membranoproliferative glomerulonephritis, membranous nephropathy), C3 glomerulopathy, atypical forms of hemolytic uremic syndrome, ischemic-reperfusion injury of transplanted kidney, and antibody-mediated renal allograft rejection are discussed. The disturbances in complement activation and regulation with underlying genetics are presented and related to observed pathology. Also promising strategies targeting the complement system in complement-related disorders are mentioned." @default.
• W2014403312 created "2016-06-24" @default.
• W2014403312 creator A5056125023 @default.
• W2014403312 creator A5058487581 @default.
• W2014403312 creator A5068371444 @default.
• W2014403312 creator A5070150486 @default.
• W2014403312 creator A5082508055 @default.
• W2014403312 date "2013-09-13" @default.
• W2014403312 modified "2023-10-11" @default.
• W2014403312 title "The Complement Cascade and Renal Disease" @default.
• W2014403312 cites W1485186526 @default.
• W2014403312 cites W1533163737 @default.
• W2014403312 cites W1565607852 @default.
• W2014403312 cites W1943879872 @default.
• W2014403312 cites W1964354023 @default.
• W2014403312 cites W1965005024 @default.
• W2014403312 cites W1966000307 @default.
• W2014403312 cites W1973896538 @default.
• W2014403312 cites W1976202743 @default.
• W2014403312 cites W1977035416 @default.
• W2014403312 cites W1981033024 @default.
• W2014403312 cites W1986341898 @default.
• W2014403312 cites W1992706312 @default.
• W2014403312 cites W1995042496 @default.
• W2014403312 cites W1997306183 @default.
• W2014403312 cites W2001882575 @default.
• W2014403312 cites W2002364878 @default.
• W2014403312 cites W2003154924 @default.
• W2014403312 cites W2005969028 @default.
• W2014403312 cites W2008607429 @default.
• W2014403312 cites W2012630248 @default.
• W2014403312 cites W2012861252 @default.
• W2014403312 cites W2017249505 @default.
• W2014403312 cites W2018971119 @default.
• W2014403312 cites W2019530336 @default.
• W2014403312 cites W2020772839 @default.
• W2014403312 cites W2021691030 @default.
• W2014403312 cites W2024751825 @default.
• W2014403312 cites W2030002999 @default.
• W2014403312 cites W2033167260 @default.
• W2014403312 cites W2033615599 @default.
• W2014403312 cites W2034860684 @default.
• W2014403312 cites W2036080352 @default.
• W2014403312 cites W2036436658 @default.
• W2014403312 cites W2047793446 @default.
• W2014403312 cites W2047798033 @default.
• W2014403312 cites W2048248583 @default.
• W2014403312 cites W2050217807 @default.
• W2014403312 cites W2052487502 @default.
• W2014403312 cites W2054101977 @default.
• W2014403312 cites W2054576721 @default.
• W2014403312 cites W2056159723 @default.
• W2014403312 cites W2058441905 @default.
• W2014403312 cites W2060044641 @default.
• W2014403312 cites W2062115674 @default.
• W2014403312 cites W2063421919 @default.
• W2014403312 cites W2064717040 @default.
• W2014403312 cites W2067092037 @default.
• W2014403312 cites W2068681520 @default.
• W2014403312 cites W2069944333 @default.
• W2014403312 cites W2070576387 @default.
• W2014403312 cites W2070836718 @default.
• W2014403312 cites W2071004236 @default.
• W2014403312 cites W2076848429 @default.
• W2014403312 cites W2077282883 @default.
• W2014403312 cites W2079362912 @default.
• W2014403312 cites W2082187912 @default.
• W2014403312 cites W2085547270 @default.
• W2014403312 cites W2086417798 @default.
• W2014403312 cites W2089013072 @default.
• W2014403312 cites W2090404552 @default.
• W2014403312 cites W2096508158 @default.
• W2014403312 cites W2101494871 @default.
• W2014403312 cites W2101666564 @default.
• W2014403312 cites W2104599968 @default.
• W2014403312 cites W2107368919 @default.
• W2014403312 cites W2107516496 @default.
• W2014403312 cites W2108609457 @default.
• W2014403312 cites W2110418515 @default.
• W2014403312 cites W2113556831 @default.
• W2014403312 cites W2118898465 @default.
• W2014403312 cites W2121291030 @default.
• W2014403312 cites W2123156974 @default.
• W2014403312 cites W2123815050 @default.
• W2014403312 cites W2126092981 @default.
• W2014403312 cites W2127321441 @default.
• W2014403312 cites W2127923616 @default.
• W2014403312 cites W2133786451 @default.
• W2014403312 cites W2138581004 @default.
• W2014403312 cites W2140297546 @default.
• W2014403312 cites W2140954411 @default.
• W2014403312 cites W2148223163 @default.
• W2014403312 cites W2154315551 @default.
• W2014403312 cites W2154713526 @default.
• W2014403312 cites W2156183571 @default.
• W2014403312 cites W2157147056 @default.
• W2014403312 cites W2157399310 @default.
• W2014403312 cites W2157622992 @default.

• next