Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014407629> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2014407629 endingPage "300" @default.
- W2014407629 startingPage "295" @default.
- W2014407629 abstract "Research on fatty acid metabolism in cultured human larynx tumor cells Hep2 was carried out. The cells were incubated with either a saturated (palmitic) or a polyunsaturated (linoleic, α -linolenic and eicosatrienoic (n-6)) radioactive fatty acid (0.66 μ M, 24 h). The best incorporation capacity was observed in the linoleic acid followed by α -linolenic, palmitic and eicosatrienoic acids. All fatty acids tested were anabolized to higher derivatives within their own family. Palmitic acid was primarily monodesaturated rather than elongated, proving to have a very active Δ 9 desaturase activity. With respect to polyunsaturated acid metabolism, the conversion of α -linolenic acid to higher homologs, although better than linoleic acid, occurred far less efficiently than that observed in other non-highly undifferentiated human tumor cells. This impairment in higher polyunsaturated fatty acid biosynthesis, reflected in the low levels of arachidonic acid in the fatty acid composition, would not reside in the Δ 5 desaturation step since Hep2 cells can readily convert eicosatrienoic acid into arachidonic acid. Considering the potential regulatory role of specific polyunsaturated fatty acids in the cell proliferative control, the knowledge of the metabolism of fatty acids in this human tumor cell would be important for designing future experiments in order to clarify the mechanism involved in balance, proliferation and cell death." @default.
- W2014407629 created "2016-06-24" @default.
- W2014407629 creator A5014315181 @default.
- W2014407629 creator A5017398014 @default.
- W2014407629 creator A5041457242 @default.
- W2014407629 creator A5064421913 @default.
- W2014407629 date "2001-11-01" @default.
- W2014407629 modified "2023-10-06" @default.
- W2014407629 title "Uptake and metabolic conversion of saturated and unsaturated fatty acids in Hep2 human larynx tumor cells" @default.
- W2014407629 cites W1590626758 @default.
- W2014407629 cites W1775749144 @default.
- W2014407629 cites W1879047861 @default.
- W2014407629 cites W189479714 @default.
- W2014407629 cites W1973425173 @default.
- W2014407629 cites W1988672861 @default.
- W2014407629 cites W2007579123 @default.
- W2014407629 cites W2012551512 @default.
- W2014407629 cites W2015112098 @default.
- W2014407629 cites W2023205648 @default.
- W2014407629 cites W2032635518 @default.
- W2014407629 cites W2034804717 @default.
- W2014407629 cites W2037238984 @default.
- W2014407629 cites W2040788523 @default.
- W2014407629 cites W2053672369 @default.
- W2014407629 cites W2057736789 @default.
- W2014407629 cites W2059576980 @default.
- W2014407629 cites W2061741222 @default.
- W2014407629 cites W2080879258 @default.
- W2014407629 cites W2086683182 @default.
- W2014407629 cites W2090333125 @default.
- W2014407629 cites W2090725184 @default.
- W2014407629 cites W2152324425 @default.
- W2014407629 cites W2168526937 @default.
- W2014407629 cites W228596548 @default.
- W2014407629 cites W2560582964 @default.
- W2014407629 doi "https://doi.org/10.1054/plef.2001.0328" @default.
- W2014407629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11993723" @default.
- W2014407629 hasPublicationYear "2001" @default.
- W2014407629 type Work @default.
- W2014407629 sameAs 2014407629 @default.
- W2014407629 citedByCount "10" @default.
- W2014407629 countsByYear W20144076292020 @default.
- W2014407629 crossrefType "journal-article" @default.
- W2014407629 hasAuthorship W2014407629A5014315181 @default.
- W2014407629 hasAuthorship W2014407629A5017398014 @default.
- W2014407629 hasAuthorship W2014407629A5041457242 @default.
- W2014407629 hasAuthorship W2014407629A5064421913 @default.
- W2014407629 hasConcept C181199279 @default.
- W2014407629 hasConcept C185592680 @default.
- W2014407629 hasConcept C19038510 @default.
- W2014407629 hasConcept C2776176469 @default.
- W2014407629 hasConcept C2776991927 @default.
- W2014407629 hasConcept C2778078955 @default.
- W2014407629 hasConcept C2779936771 @default.
- W2014407629 hasConcept C2780809830 @default.
- W2014407629 hasConcept C3020713888 @default.
- W2014407629 hasConcept C543025807 @default.
- W2014407629 hasConcept C55493867 @default.
- W2014407629 hasConcept C62231903 @default.
- W2014407629 hasConcept C86803240 @default.
- W2014407629 hasConceptScore W2014407629C181199279 @default.
- W2014407629 hasConceptScore W2014407629C185592680 @default.
- W2014407629 hasConceptScore W2014407629C19038510 @default.
- W2014407629 hasConceptScore W2014407629C2776176469 @default.
- W2014407629 hasConceptScore W2014407629C2776991927 @default.
- W2014407629 hasConceptScore W2014407629C2778078955 @default.
- W2014407629 hasConceptScore W2014407629C2779936771 @default.
- W2014407629 hasConceptScore W2014407629C2780809830 @default.
- W2014407629 hasConceptScore W2014407629C3020713888 @default.
- W2014407629 hasConceptScore W2014407629C543025807 @default.
- W2014407629 hasConceptScore W2014407629C55493867 @default.
- W2014407629 hasConceptScore W2014407629C62231903 @default.
- W2014407629 hasConceptScore W2014407629C86803240 @default.
- W2014407629 hasIssue "5-6" @default.
- W2014407629 hasLocation W20144076291 @default.
- W2014407629 hasLocation W20144076292 @default.
- W2014407629 hasOpenAccess W2014407629 @default.
- W2014407629 hasPrimaryLocation W20144076291 @default.
- W2014407629 hasRelatedWork W1966894645 @default.
- W2014407629 hasRelatedWork W1979589073 @default.
- W2014407629 hasRelatedWork W2014407629 @default.
- W2014407629 hasRelatedWork W2037992742 @default.
- W2014407629 hasRelatedWork W2041770204 @default.
- W2014407629 hasRelatedWork W2058281307 @default.
- W2014407629 hasRelatedWork W2063764239 @default.
- W2014407629 hasRelatedWork W2082449879 @default.
- W2014407629 hasRelatedWork W2351310494 @default.
- W2014407629 hasRelatedWork W2963926168 @default.
- W2014407629 hasVolume "65" @default.
- W2014407629 isParatext "false" @default.
- W2014407629 isRetracted "false" @default.
- W2014407629 magId "2014407629" @default.
- W2014407629 workType "article" @default.