Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014429487> ?p ?o ?g. }
- W2014429487 endingPage "795" @default.
- W2014429487 startingPage "791" @default.
- W2014429487 abstract "An extract of Citrus sinensis (CS) peel was evaluated for its efficacy in ameliorating L-thyroxine (L-T4) induced tissue lipid peroxidation (LPO), hyperthyroidism and hyperglycemia in mice. In a preliminary investigation, of the three different doses of CS (12.5 mg/kg, 25 mg/kg and 50.0 mg/kg) peel extract, 25 mg/kg was found to be the most effective and antiperoxidative, while 50 mg/kg was proved to be hepatotoxic. Therefore in the pilot experiment the effects of 25 mg/kg/day of CS for 10 days were studied in L-T4 induced hyperthyroid animals. L-T4 (500 µg/kg/day for 10 days) increased the levels of thyroxine (T4) and triiodothyronine (T3) with a concomitant increase in serum glucose concentration, alpha-amylase activity, heart/body weight ratio (HW/BW), kidney/body weight ratio (KW/BW) and cardiac as well as hepatic LPO. However, it decreased the concentration of different serum lipids such as total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C). Administration of CS extract (25 mg/kg/day) in hyperthyroid animals reversed most of these observations revealing the ameliorating potential of CS extract against various adverse effects of hyperthyroidism. It appears that the test extract primarily acts through its antioxidative/free radical-scavenging, antithyroidal and HDL-C stimulating properties. Copyright © 2008 John Wiley & Sons, Ltd." @default.
- W2014429487 created "2016-06-24" @default.
- W2014429487 creator A5011568866 @default.
- W2014429487 creator A5044717410 @default.
- W2014429487 date "2008-01-01" @default.
- W2014429487 modified "2023-10-03" @default.
- W2014429487 title "Antiperoxidative, antithyroidal, antihyperglycemic and cardioprotective role ofCitrus sinensis peel extract in male mice" @default.
- W2014429487 cites W173609656 @default.
- W2014429487 cites W1775749144 @default.
- W2014429487 cites W1967073560 @default.
- W2014429487 cites W1973673414 @default.
- W2014429487 cites W1999630897 @default.
- W2014429487 cites W2003666588 @default.
- W2014429487 cites W2006370393 @default.
- W2014429487 cites W2016045293 @default.
- W2014429487 cites W2025387214 @default.
- W2014429487 cites W2036680180 @default.
- W2014429487 cites W2046105635 @default.
- W2014429487 cites W2057012523 @default.
- W2014429487 cites W2062326309 @default.
- W2014429487 cites W2067796323 @default.
- W2014429487 cites W2068731305 @default.
- W2014429487 cites W2074250415 @default.
- W2014429487 cites W2086069728 @default.
- W2014429487 cites W2094260719 @default.
- W2014429487 cites W2103734592 @default.
- W2014429487 cites W2116404316 @default.
- W2014429487 cites W2126597415 @default.
- W2014429487 cites W2139408780 @default.
- W2014429487 cites W2150898264 @default.
- W2014429487 cites W2321638789 @default.
- W2014429487 cites W267337293 @default.
- W2014429487 doi "https://doi.org/10.1002/ptr.2367" @default.
- W2014429487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18412146" @default.
- W2014429487 hasPublicationYear "2008" @default.
- W2014429487 type Work @default.
- W2014429487 sameAs 2014429487 @default.
- W2014429487 citedByCount "41" @default.
- W2014429487 countsByYear W20144294872012 @default.
- W2014429487 countsByYear W20144294872013 @default.
- W2014429487 countsByYear W20144294872014 @default.
- W2014429487 countsByYear W20144294872015 @default.
- W2014429487 countsByYear W20144294872016 @default.
- W2014429487 countsByYear W20144294872017 @default.
- W2014429487 countsByYear W20144294872018 @default.
- W2014429487 countsByYear W20144294872019 @default.
- W2014429487 countsByYear W20144294872020 @default.
- W2014429487 countsByYear W20144294872021 @default.
- W2014429487 countsByYear W20144294872022 @default.
- W2014429487 countsByYear W20144294872023 @default.
- W2014429487 crossrefType "journal-article" @default.
- W2014429487 hasAuthorship W2014429487A5011568866 @default.
- W2014429487 hasAuthorship W2014429487A5044717410 @default.
- W2014429487 hasConcept C126322002 @default.
- W2014429487 hasConcept C134018914 @default.
- W2014429487 hasConcept C185592680 @default.
- W2014429487 hasConcept C2778004101 @default.
- W2014429487 hasConcept C2778163477 @default.
- W2014429487 hasConcept C2778288131 @default.
- W2014429487 hasConcept C2780072125 @default.
- W2014429487 hasConcept C2780541478 @default.
- W2014429487 hasConcept C2780829032 @default.
- W2014429487 hasConcept C526584372 @default.
- W2014429487 hasConcept C55493867 @default.
- W2014429487 hasConcept C71924100 @default.
- W2014429487 hasConcept C8243546 @default.
- W2014429487 hasConceptScore W2014429487C126322002 @default.
- W2014429487 hasConceptScore W2014429487C134018914 @default.
- W2014429487 hasConceptScore W2014429487C185592680 @default.
- W2014429487 hasConceptScore W2014429487C2778004101 @default.
- W2014429487 hasConceptScore W2014429487C2778163477 @default.
- W2014429487 hasConceptScore W2014429487C2778288131 @default.
- W2014429487 hasConceptScore W2014429487C2780072125 @default.
- W2014429487 hasConceptScore W2014429487C2780541478 @default.
- W2014429487 hasConceptScore W2014429487C2780829032 @default.
- W2014429487 hasConceptScore W2014429487C526584372 @default.
- W2014429487 hasConceptScore W2014429487C55493867 @default.
- W2014429487 hasConceptScore W2014429487C71924100 @default.
- W2014429487 hasConceptScore W2014429487C8243546 @default.
- W2014429487 hasIssue "6" @default.
- W2014429487 hasLocation W20144294871 @default.
- W2014429487 hasLocation W20144294872 @default.
- W2014429487 hasOpenAccess W2014429487 @default.
- W2014429487 hasPrimaryLocation W20144294871 @default.
- W2014429487 hasRelatedWork W1976602105 @default.
- W2014429487 hasRelatedWork W1993860810 @default.
- W2014429487 hasRelatedWork W2025648868 @default.
- W2014429487 hasRelatedWork W2083791620 @default.
- W2014429487 hasRelatedWork W2118738696 @default.
- W2014429487 hasRelatedWork W2157000830 @default.
- W2014429487 hasRelatedWork W2157155183 @default.
- W2014429487 hasRelatedWork W2413861530 @default.
- W2014429487 hasRelatedWork W2748952813 @default.
- W2014429487 hasRelatedWork W4244653511 @default.
- W2014429487 hasVolume "22" @default.
- W2014429487 isParatext "false" @default.
- W2014429487 isRetracted "false" @default.
- W2014429487 magId "2014429487" @default.