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- W2014450807 abstract "With the aim of studying the involvement of the mitochondrial genome in the impairment of heart function, mitochondrial DNA was analyzed by modified primer shift-polymerase chain reaction in a panel of young patients affected by primary cardiomyopathies. Mitochondrial DNA molecules harboring the 7436 bp deletion were specifically found in cardiomyopathic patients as compared with a panel of control subjects. The 4977 bp deletion was commonly detected among the subjects analyzed whereas none of the specific tRNA gene point mutations generally associated with the cardiomyopathic trait were detected. The presence of the 7436 bp deletion as a consequence of a premature aging of the heart muscle, secondary to heart dysfunction, is discussed." @default.
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- W2014450807 date "1995-12-01" @default.
- W2014450807 modified "2023-10-17" @default.
- W2014450807 title "Characterization of mitochondrial DNA in primary cardiomyopathies" @default.
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- W2014450807 doi "https://doi.org/10.1016/0009-8981(95)06166-5" @default.
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