FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014455032> ?p ?o ?g. }

• W2014455032 endingPage "640" @default.
• W2014455032 startingPage "635" @default.
• W2014455032 abstract "The renin–angiotensin-system cascade pathway generates the vasopressor and prothrombotic hormones, angiotensin II (Ang II) and angiotensin III (Ang III) from angiotensinogen. One of the key enzymes for the generation of angiotensin 1–7 (Ang 1–7) and angiotensin 2–7 (Ang 2–7) from Ang II and III, respectively, is prolylcarboxypeptidase (PRCP). To understand the contribution of the N-terminal region to catalysis, an N-terminal truncated form, lacking 179 N-terminal residues of PRCP (rPRCP40) was constructed. The circular dichroism (CD) spectrum of rPRCP40 illustrated that it was structured with significant helical content as indicated by local minima at ∼220 and 208 nm. The main products of Ang III metabolized by rPRCP40 were Ang 2–7 plus phenylalanine as determined by LC–MS. Angiotensin I (Ang I) blocked the metabolism of Ang III by rPRCP40. These investigations showed that the C-terminal region of the rPRCP40 contributes to PRCP’s catalytic function, and provided additional experimental evidence for this suggestion." @default.
• W2014455032 created "2016-06-24" @default.
• W2014455032 creator A5002861368 @default.
• W2014455032 creator A5041861134 @default.
• W2014455032 creator A5080427926 @default.
• W2014455032 creator A5081038993 @default.
• W2014455032 creator A5082537523 @default.
• W2014455032 creator A5089123215 @default.
• W2014455032 date "2008-10-01" @default.
• W2014455032 modified "2023-10-17" @default.
• W2014455032 title "The functional importance of the N-terminal region of human prolylcarboxypeptidase" @default.
• W2014455032 cites W1496368635 @default.
• W2014455032 cites W1500912019 @default.
• W2014455032 cites W1550418875 @default.
• W2014455032 cites W1997605926 @default.
• W2014455032 cites W2015437707 @default.
• W2014455032 cites W2017997696 @default.
• W2014455032 cites W2037869599 @default.
• W2014455032 cites W2042767397 @default.
• W2014455032 cites W2046090148 @default.
• W2014455032 cites W2049703801 @default.
• W2014455032 cites W2052726096 @default.
• W2014455032 cites W2054633565 @default.
• W2014455032 cites W2096590542 @default.
• W2014455032 cites W2099893465 @default.
• W2014455032 cites W2104017463 @default.
• W2014455032 cites W864057789 @default.
• W2014455032 doi "https://doi.org/10.1016/j.bbrc.2008.07.069" @default.
• W2014455032 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2561253" @default.
• W2014455032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18656443" @default.
• W2014455032 hasPublicationYear "2008" @default.
• W2014455032 type Work @default.
• W2014455032 sameAs 2014455032 @default.
• W2014455032 citedByCount "12" @default.
• W2014455032 countsByYear W20144550322012 @default.
• W2014455032 countsByYear W20144550322013 @default.
• W2014455032 countsByYear W20144550322015 @default.
• W2014455032 countsByYear W20144550322022 @default.
• W2014455032 crossrefType "journal-article" @default.
• W2014455032 hasAuthorship W2014455032A5002861368 @default.
• W2014455032 hasAuthorship W2014455032A5041861134 @default.
• W2014455032 hasAuthorship W2014455032A5080427926 @default.
• W2014455032 hasAuthorship W2014455032A5081038993 @default.
• W2014455032 hasAuthorship W2014455032A5082537523 @default.
• W2014455032 hasAuthorship W2014455032A5089123215 @default.
• W2014455032 hasBestOaLocation W20144550322 @default.
• W2014455032 hasConcept C123915805 @default.
• W2014455032 hasConcept C126322002 @default.
• W2014455032 hasConcept C134018914 @default.
• W2014455032 hasConcept C161790260 @default.
• W2014455032 hasConcept C170493617 @default.
• W2014455032 hasConcept C181199279 @default.
• W2014455032 hasConcept C185592680 @default.
• W2014455032 hasConcept C198710026 @default.
• W2014455032 hasConcept C2779664074 @default.
• W2014455032 hasConcept C2908560794 @default.
• W2014455032 hasConcept C2908929049 @default.
• W2014455032 hasConcept C41008148 @default.
• W2014455032 hasConcept C55493867 @default.
• W2014455032 hasConcept C71315377 @default.
• W2014455032 hasConcept C71924100 @default.
• W2014455032 hasConcept C76155785 @default.
• W2014455032 hasConcept C84393581 @default.
• W2014455032 hasConcept C86803240 @default.
• W2014455032 hasConceptScore W2014455032C123915805 @default.
• W2014455032 hasConceptScore W2014455032C126322002 @default.
• W2014455032 hasConceptScore W2014455032C134018914 @default.
• W2014455032 hasConceptScore W2014455032C161790260 @default.
• W2014455032 hasConceptScore W2014455032C170493617 @default.
• W2014455032 hasConceptScore W2014455032C181199279 @default.
• W2014455032 hasConceptScore W2014455032C185592680 @default.
• W2014455032 hasConceptScore W2014455032C198710026 @default.
• W2014455032 hasConceptScore W2014455032C2779664074 @default.
• W2014455032 hasConceptScore W2014455032C2908560794 @default.
• W2014455032 hasConceptScore W2014455032C2908929049 @default.
• W2014455032 hasConceptScore W2014455032C41008148 @default.
• W2014455032 hasConceptScore W2014455032C55493867 @default.
• W2014455032 hasConceptScore W2014455032C71315377 @default.
• W2014455032 hasConceptScore W2014455032C71924100 @default.
• W2014455032 hasConceptScore W2014455032C76155785 @default.
• W2014455032 hasConceptScore W2014455032C84393581 @default.
• W2014455032 hasConceptScore W2014455032C86803240 @default.
• W2014455032 hasIssue "4" @default.
• W2014455032 hasLocation W20144550321 @default.
• W2014455032 hasLocation W20144550322 @default.
• W2014455032 hasLocation W20144550323 @default.
• W2014455032 hasLocation W20144550324 @default.
• W2014455032 hasOpenAccess W2014455032 @default.
• W2014455032 hasPrimaryLocation W20144550321 @default.
• W2014455032 hasRelatedWork W2001195849 @default.
• W2014455032 hasRelatedWork W2029456335 @default.
• W2014455032 hasRelatedWork W2071203182 @default.
• W2014455032 hasRelatedWork W2078974031 @default.
• W2014455032 hasRelatedWork W2079695385 @default.
• W2014455032 hasRelatedWork W2146731820 @default.
• W2014455032 hasRelatedWork W2315771027 @default.
• W2014455032 hasRelatedWork W2334489117 @default.
• W2014455032 hasRelatedWork W2364563709 @default.

• next