Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014486743> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2014486743 endingPage "131" @default.
- W2014486743 startingPage "128" @default.
- W2014486743 abstract "Careful interpretation of discordant results in high-sensitivity troponin measurements is necessary in cases of suspect immunoassay interferences. We describe several procedures taken in a case of a polymorbid patient with chest pain, without clear evidence of myocardial necrosis and with increased high-sensitivity cardiac troponin T (hs-cTnT). We checked the Vafaie's algorithm for the evaluation of suspect interference in troponin measurements. We conducted a case report analysis, additional measurements, a dilution test and pretreatment of plasma with blocking agents. Concentration of hs-cTnT (99th percentile of “healthy” population 14 ng/L) increased from 120.1 ng/L to 280.4 ng/L during an 8-month period and decreased to 216.3 ng/L during the following month with repeatedly negative troponin I (TnI), hs-cTnI, myoglobin and creatine kinase MB (CK-MB). Suspected false positivity of hs-cTnT was further confirmed by treatment of plasma with an antiheterophile blocking agent (hs-cTnT before treatment 280.4 ng/L, after 16.53/16.23 ng/L). This outcome was further confirmed by the manufacturer's experiments. The false-positive results of hs-cTnT were caused by the presence of extremely rare high molecular weight protein, presumably IgM, most likely HAMA (human anti-mouse antibody). Only the pre-treatment of plasma with a blocking agent provided a reliable indication of the interference. Cooperation among clinicians, laboratory personnel and the manufacturer is essential." @default.
- W2014486743 created "2016-06-24" @default.
- W2014486743 creator A5007136304 @default.
- W2014486743 creator A5007728848 @default.
- W2014486743 creator A5016937291 @default.
- W2014486743 creator A5023597608 @default.
- W2014486743 creator A5037543643 @default.
- W2014486743 creator A5051078731 @default.
- W2014486743 creator A5077181000 @default.
- W2014486743 creator A5089588573 @default.
- W2014486743 date "2015-06-01" @default.
- W2014486743 modified "2023-10-18" @default.
- W2014486743 title "A clinical and laboratory approach used to elucidate discordant results of high-sensitivity troponin T and troponin I" @default.
- W2014486743 cites W1970428090 @default.
- W2014486743 cites W2006697669 @default.
- W2014486743 cites W2014441305 @default.
- W2014486743 cites W2073241303 @default.
- W2014486743 cites W2080917274 @default.
- W2014486743 cites W2098556604 @default.
- W2014486743 cites W2109389763 @default.
- W2014486743 cites W2119556721 @default.
- W2014486743 cites W2133177813 @default.
- W2014486743 cites W2139913043 @default.
- W2014486743 cites W2144869046 @default.
- W2014486743 cites W2151231511 @default.
- W2014486743 cites W2168794783 @default.
- W2014486743 cites W2169101225 @default.
- W2014486743 cites W2325763399 @default.
- W2014486743 doi "https://doi.org/10.1016/j.cca.2015.03.046" @default.
- W2014486743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25896964" @default.
- W2014486743 hasPublicationYear "2015" @default.
- W2014486743 type Work @default.
- W2014486743 sameAs 2014486743 @default.
- W2014486743 citedByCount "9" @default.
- W2014486743 countsByYear W20144867432015 @default.
- W2014486743 countsByYear W20144867432017 @default.
- W2014486743 countsByYear W20144867432018 @default.
- W2014486743 countsByYear W20144867432019 @default.
- W2014486743 countsByYear W20144867432020 @default.
- W2014486743 crossrefType "journal-article" @default.
- W2014486743 hasAuthorship W2014486743A5007136304 @default.
- W2014486743 hasAuthorship W2014486743A5007728848 @default.
- W2014486743 hasAuthorship W2014486743A5016937291 @default.
- W2014486743 hasAuthorship W2014486743A5023597608 @default.
- W2014486743 hasAuthorship W2014486743A5037543643 @default.
- W2014486743 hasAuthorship W2014486743A5051078731 @default.
- W2014486743 hasAuthorship W2014486743A5077181000 @default.
- W2014486743 hasAuthorship W2014486743A5089588573 @default.
- W2014486743 hasConcept C115725540 @default.
- W2014486743 hasConcept C126322002 @default.
- W2014486743 hasConcept C144469398 @default.
- W2014486743 hasConcept C159654299 @default.
- W2014486743 hasConcept C164705383 @default.
- W2014486743 hasConcept C203014093 @default.
- W2014486743 hasConcept C2780420688 @default.
- W2014486743 hasConcept C2908647359 @default.
- W2014486743 hasConcept C2909597000 @default.
- W2014486743 hasConcept C36036425 @default.
- W2014486743 hasConcept C36880943 @default.
- W2014486743 hasConcept C500558357 @default.
- W2014486743 hasConcept C71924100 @default.
- W2014486743 hasConcept C8880881 @default.
- W2014486743 hasConcept C99454951 @default.
- W2014486743 hasConceptScore W2014486743C115725540 @default.
- W2014486743 hasConceptScore W2014486743C126322002 @default.
- W2014486743 hasConceptScore W2014486743C144469398 @default.
- W2014486743 hasConceptScore W2014486743C159654299 @default.
- W2014486743 hasConceptScore W2014486743C164705383 @default.
- W2014486743 hasConceptScore W2014486743C203014093 @default.
- W2014486743 hasConceptScore W2014486743C2780420688 @default.
- W2014486743 hasConceptScore W2014486743C2908647359 @default.
- W2014486743 hasConceptScore W2014486743C2909597000 @default.
- W2014486743 hasConceptScore W2014486743C36036425 @default.
- W2014486743 hasConceptScore W2014486743C36880943 @default.
- W2014486743 hasConceptScore W2014486743C500558357 @default.
- W2014486743 hasConceptScore W2014486743C71924100 @default.
- W2014486743 hasConceptScore W2014486743C8880881 @default.
- W2014486743 hasConceptScore W2014486743C99454951 @default.
- W2014486743 hasLocation W20144867431 @default.
- W2014486743 hasLocation W20144867432 @default.
- W2014486743 hasOpenAccess W2014486743 @default.
- W2014486743 hasPrimaryLocation W20144867431 @default.
- W2014486743 hasRelatedWork W1918982458 @default.
- W2014486743 hasRelatedWork W2003472806 @default.
- W2014486743 hasRelatedWork W2014486743 @default.
- W2014486743 hasRelatedWork W2028971149 @default.
- W2014486743 hasRelatedWork W2058888796 @default.
- W2014486743 hasRelatedWork W207789239 @default.
- W2014486743 hasRelatedWork W2081076442 @default.
- W2014486743 hasRelatedWork W2160781552 @default.
- W2014486743 hasRelatedWork W2163055393 @default.
- W2014486743 hasRelatedWork W2409002227 @default.
- W2014486743 hasVolume "446" @default.
- W2014486743 isParatext "false" @default.
- W2014486743 isRetracted "false" @default.
- W2014486743 magId "2014486743" @default.
- W2014486743 workType "article" @default.