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- W2014504531 abstract "Azathioprine and cyclophosphamide in doses of 3 mg/kg were assessed in humans with immunopathic diseases in respect to effects on humoral antibody production and counts of antigen-binding lymphocytes in blood, using flagellin as test antigen. The results for azathioprine-treated patients did not differ significantly from those for nontreated control patients, whereas for cyclophosphamide-treated patients there was significant suppression of humoral antibody to flagellin, especially IgG, and no increase in antigen-binding lymphocytes in blood after immunization. These and other observations, relating to inhibitory effects of azathioprine on T cells and antiproliferative effects of cyclophosphamide on B cells, could have implications for therapy of immunopathic diseases." @default.
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- W2014504531 date "1973-07-01" @default.
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- W2014504531 title "Differing Effects of Azathioprine and Cyclophosphamide on Immune Responses to Flagellin in Man" @default.
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- W2014504531 doi "https://doi.org/10.1002/art.1780160404" @default.
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