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• W2014513507 abstract "Calprotectin is produced by activated monocytes and microglia, and cerebrospinal fluid (CSF) levels could be a marker of neuroinflammation. Calprotectin was detectable in CSF from 13.8% of normal controls, compared to 90.5% of patients with neurological infections (p<0.001). In CSF from patients with multiple sclerosis (MS) and clinically isolated demyelinating syndrome, calprotectin was detected in 64.7% within 2 weeks after symptom debut compared to 30.8% between 2 and 4 weeks and 17.0% thereafter (p<0.001). We conclude that CSF calprotectin reflects the disease activity in MS but does not discriminate between MS and other inflammatory or infectious conditions." @default.
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• W2014513507 date "2009-11-30" @default.
• W2014513507 modified "2023-09-27" @default.
• W2014513507 title "Calprotectin levels in the cerebrospinal fluid reflect disease activity in multiple sclerosis" @default.
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• W2014513507 doi "https://doi.org/10.1016/j.jneuroim.2009.09.006" @default.
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