Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014513813> ?p ?o ?g. }
- W2014513813 endingPage "579" @default.
- W2014513813 startingPage "571" @default.
- W2014513813 abstract "Patients with dementia with Lewy bodies (DLB) commonly experience psychotic symptoms, most notably visual hallucinations. Previously, it has been shown that visual hallucinations in DLB are associated with reduced cortical choline acetyltransferase activity, a marker of cholinergic innervation, but not with predominantly postsynaptic muscarinic M1 receptor binding. In the present investigation, nicotinic acetylcholine receptor (nAChR) levels in the temporal cortex (Brodmann's areas [BA] 20 and 36) were measured in a group of 24 prospectively assessed DLB patients; comparisons were made between groups with or without visual and auditory hallucinations and delusional misidentification. Visual hallucinations and delusional misidentification were associated with lower [(125)I]alpha bungarotoxin binding in areas 36 and 20 (P<.05), but not with changes in [(3)H]epibatidine binding. There were no significant associations with auditory hallucinations. [(3)H]epibatidine, but not [(125)I]alpha bungarotoxin, binding for all DLB cases was reduced compared to controls (P<.001). Loss of cortical alpha 7 nicotinic receptors may contribute to hallucinations and delusional misidentification in DLB, with implications for treatment and understanding the mechanisms of psychotic symptoms in dementia." @default.
- W2014513813 created "2016-06-24" @default.
- W2014513813 creator A5001741634 @default.
- W2014513813 creator A5008386494 @default.
- W2014513813 creator A5012877366 @default.
- W2014513813 creator A5027987037 @default.
- W2014513813 creator A5032708452 @default.
- W2014513813 creator A5049094607 @default.
- W2014513813 creator A5054997532 @default.
- W2014513813 creator A5064532444 @default.
- W2014513813 creator A5069797552 @default.
- W2014513813 creator A5072010327 @default.
- W2014513813 creator A5091136172 @default.
- W2014513813 date "2001-12-01" @default.
- W2014513813 modified "2023-10-18" @default.
- W2014513813 title "Visual hallucinations are associated with lower αbungarotoxin binding in dementia with Lewy bodies" @default.
- W2014513813 cites W1688235741 @default.
- W2014513813 cites W1884672048 @default.
- W2014513813 cites W1963979286 @default.
- W2014513813 cites W1964178477 @default.
- W2014513813 cites W1964593020 @default.
- W2014513813 cites W1966103309 @default.
- W2014513813 cites W1970110793 @default.
- W2014513813 cites W1976012908 @default.
- W2014513813 cites W1984475571 @default.
- W2014513813 cites W1995735916 @default.
- W2014513813 cites W1999593494 @default.
- W2014513813 cites W2013231002 @default.
- W2014513813 cites W2016659621 @default.
- W2014513813 cites W2017291778 @default.
- W2014513813 cites W2018532232 @default.
- W2014513813 cites W2020358225 @default.
- W2014513813 cites W2020370964 @default.
- W2014513813 cites W2020848554 @default.
- W2014513813 cites W2021108610 @default.
- W2014513813 cites W2021139758 @default.
- W2014513813 cites W2030494905 @default.
- W2014513813 cites W2034172776 @default.
- W2014513813 cites W2046245590 @default.
- W2014513813 cites W2052115885 @default.
- W2014513813 cites W2052742260 @default.
- W2014513813 cites W2055160638 @default.
- W2014513813 cites W2059147823 @default.
- W2014513813 cites W2063359456 @default.
- W2014513813 cites W2069080061 @default.
- W2014513813 cites W2070665867 @default.
- W2014513813 cites W2077730162 @default.
- W2014513813 cites W2081800196 @default.
- W2014513813 cites W2088919930 @default.
- W2014513813 cites W2090019512 @default.
- W2014513813 cites W2090502324 @default.
- W2014513813 cites W2090942238 @default.
- W2014513813 cites W2091240406 @default.
- W2014513813 cites W2092767820 @default.
- W2014513813 cites W2094815523 @default.
- W2014513813 cites W2095022929 @default.
- W2014513813 cites W2095124166 @default.
- W2014513813 cites W2103514611 @default.
- W2014513813 cites W2118050758 @default.
- W2014513813 cites W2123056519 @default.
- W2014513813 cites W2137566057 @default.
- W2014513813 cites W2138627575 @default.
- W2014513813 cites W2144671685 @default.
- W2014513813 cites W2145262930 @default.
- W2014513813 cites W2146729934 @default.
- W2014513813 cites W2150957783 @default.
- W2014513813 cites W2161480337 @default.
- W2014513813 cites W2311204851 @default.
- W2014513813 cites W4317639052 @default.
- W2014513813 doi "https://doi.org/10.1016/s0091-3057(01)00644-x" @default.
- W2014513813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11796155" @default.
- W2014513813 hasPublicationYear "2001" @default.
- W2014513813 type Work @default.
- W2014513813 sameAs 2014513813 @default.
- W2014513813 citedByCount "51" @default.
- W2014513813 countsByYear W20145138132012 @default.
- W2014513813 countsByYear W20145138132013 @default.
- W2014513813 countsByYear W20145138132014 @default.
- W2014513813 countsByYear W20145138132015 @default.
- W2014513813 countsByYear W20145138132016 @default.
- W2014513813 countsByYear W20145138132017 @default.
- W2014513813 countsByYear W20145138132018 @default.
- W2014513813 countsByYear W20145138132019 @default.
- W2014513813 countsByYear W20145138132020 @default.
- W2014513813 countsByYear W20145138132021 @default.
- W2014513813 countsByYear W20145138132023 @default.
- W2014513813 crossrefType "journal-article" @default.
- W2014513813 hasAuthorship W2014513813A5001741634 @default.
- W2014513813 hasAuthorship W2014513813A5008386494 @default.
- W2014513813 hasAuthorship W2014513813A5012877366 @default.
- W2014513813 hasAuthorship W2014513813A5027987037 @default.
- W2014513813 hasAuthorship W2014513813A5032708452 @default.
- W2014513813 hasAuthorship W2014513813A5049094607 @default.
- W2014513813 hasAuthorship W2014513813A5054997532 @default.
- W2014513813 hasAuthorship W2014513813A5064532444 @default.
- W2014513813 hasAuthorship W2014513813A5069797552 @default.
- W2014513813 hasAuthorship W2014513813A5072010327 @default.
- W2014513813 hasAuthorship W2014513813A5091136172 @default.