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- W2014520738 abstract "The effects of monoclonal antibody to the T200 antigen on murine mixed-lymphocyte cultures (MLC) and on the generation of alloreactive cytotoxic T lymphocytes (CTL) are investigated. Addition of monoclonal anti-T200 without complement to MLC results in a late suppression of the proliferative response preceded in some cases by an early enhancement. These modulations require the presence of allogeneic stimulator cells; no effects are seen when antibody is added to responders alone. A similar effect is seen on the generation of CTL. Compared to controls without antibody, cultures carried out in the presence of anti-T200 show reduced levels of cytotoxicity measured against allogeneic targets by Day 5. The kinetics of the suppressive effects differ from those seen with anti-Lyt-2, and no suppressive effects are seen with monoclonal antibodies to other cell surface molecules." @default.
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- W2014520738 date "1983-10-01" @default.
- W2014520738 modified "2023-10-14" @default.
- W2014520738 title "Modulation of in vitro immune responses by monoclonal antibody to T200 antigen" @default.
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- W2014520738 doi "https://doi.org/10.1016/0008-8749(83)90212-5" @default.
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