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- W2014535178 abstract "Purpose of review Glucocorticoids are frequently used in the treatment of patients with neurooncological disorders. This review addresses different clinical indications and provides information on beneficial and undesired effects exerted by these drugs. The most important cellular mechanisms of action of glucocorticoids under different conditions are highlighted. Recent findings Glucocorticoids have been used for the treatment of lymphoid neoplasms for decades. In addition to proapoptotic effects, recent studies have delineated the induction of autophagy in lymphoma cells as an important alternative mode of cell death. In contrast, glucocorticoids may reduce the sensitivity of tumor cells, including glioma cells, other than lymphoma cells to chemotherapeutic agents. Corticosteroids also provide transient relief from neurological symptoms caused by increased intracranial pressure and edema associated with primary and secondary brain tumors. However, treatment with glucocorticoids is also commonly associated with considerable side-effects including hyperglycemia, myopathy, osteoporosis, lymphopenia and others. Summary Although in clinical use for more than 40 years in the field of neurooncology, steroids remain a central and essential part in the treatment of brain tumor patients. Along with improved therapeutic options and prolonged life expectancy of many of these patients, careful administration is required and long-term side-effects must be considered." @default.
- W2014535178 created "2016-06-24" @default.
- W2014535178 creator A5017177249 @default.
- W2014535178 creator A5044206440 @default.
- W2014535178 creator A5080482957 @default.
- W2014535178 date "2010-12-01" @default.
- W2014535178 modified "2023-10-18" @default.
- W2014535178 title "Steroids in neurooncology: actions, indications, side-effects" @default.
- W2014535178 cites W1010417915 @default.
- W2014535178 cites W1517353469 @default.
- W2014535178 cites W1544190631 @default.
- W2014535178 cites W1568042534 @default.
- W2014535178 cites W1973138364 @default.
- W2014535178 cites W1975295807 @default.
- W2014535178 cites W1981528515 @default.
- W2014535178 cites W1983216934 @default.
- W2014535178 cites W1989786947 @default.
- W2014535178 cites W1990503775 @default.
- W2014535178 cites W1998210173 @default.
- W2014535178 cites W1999179879 @default.
- W2014535178 cites W2000297826 @default.
- W2014535178 cites W2000948536 @default.
- W2014535178 cites W2001589253 @default.
- W2014535178 cites W2002056663 @default.
- W2014535178 cites W2002315967 @default.
- W2014535178 cites W2005169943 @default.
- W2014535178 cites W2007919969 @default.
- W2014535178 cites W2008106123 @default.
- W2014535178 cites W2009916434 @default.
- W2014535178 cites W2010243444 @default.
- W2014535178 cites W2010450340 @default.
- W2014535178 cites W2011203192 @default.
- W2014535178 cites W2011366383 @default.
- W2014535178 cites W2014498328 @default.
- W2014535178 cites W2020896282 @default.
- W2014535178 cites W2021456179 @default.
- W2014535178 cites W2023709249 @default.
- W2014535178 cites W2030573007 @default.
- W2014535178 cites W2031026757 @default.
- W2014535178 cites W2032080629 @default.
- W2014535178 cites W2033369193 @default.
- W2014535178 cites W2035409850 @default.
- W2014535178 cites W2037646172 @default.
- W2014535178 cites W2040010289 @default.
- W2014535178 cites W2042007405 @default.
- W2014535178 cites W2044672640 @default.
- W2014535178 cites W2050682684 @default.
- W2014535178 cites W2054461022 @default.
- W2014535178 cites W2060549911 @default.
- W2014535178 cites W2061878363 @default.
- W2014535178 cites W2061929833 @default.
- W2014535178 cites W2066792372 @default.
- W2014535178 cites W2067399509 @default.
- W2014535178 cites W2068475145 @default.
- W2014535178 cites W2069729406 @default.
- W2014535178 cites W2072260146 @default.
- W2014535178 cites W2074658917 @default.
- W2014535178 cites W2075959152 @default.
- W2014535178 cites W2078581194 @default.
- W2014535178 cites W2079325679 @default.
- W2014535178 cites W2082981537 @default.
- W2014535178 cites W2084856835 @default.
- W2014535178 cites W2085286861 @default.
- W2014535178 cites W2085404811 @default.
- W2014535178 cites W2087669700 @default.
- W2014535178 cites W2089081917 @default.
- W2014535178 cites W2091135494 @default.
- W2014535178 cites W2098940314 @default.
- W2014535178 cites W2107621783 @default.
- W2014535178 cites W2113906101 @default.
- W2014535178 cites W2121006344 @default.
- W2014535178 cites W2122687151 @default.
- W2014535178 cites W2124483143 @default.
- W2014535178 cites W2124596819 @default.
- W2014535178 cites W2128687105 @default.
- W2014535178 cites W2129617373 @default.
- W2014535178 cites W2132697290 @default.
- W2014535178 cites W2135178872 @default.
- W2014535178 cites W2135453454 @default.
- W2014535178 cites W2135907153 @default.
- W2014535178 cites W2143737320 @default.
- W2014535178 cites W2150080078 @default.
- W2014535178 cites W2155943684 @default.
- W2014535178 cites W2159941636 @default.
- W2014535178 cites W2166696317 @default.
- W2014535178 cites W2167033587 @default.
- W2014535178 cites W2170891429 @default.
- W2014535178 cites W2171133944 @default.
- W2014535178 doi "https://doi.org/10.1097/wco.0b013e32833e5a5d" @default.
- W2014535178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20962642" @default.
- W2014535178 hasPublicationYear "2010" @default.
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