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• W2014549199 endingPage "291" @default.
• W2014549199 startingPage "283" @default.
• W2014549199 abstract "The chicken immunoglobulin lambda locus contains a single C lambda gene with a unique J lambda element, 1.9 kb upstream. The same V lambda gene (V lambda 1) is rearranged in most cells of the Bursa of Fabricius. This V lambda 1 gene is located, in germ-line configuration, 1.7 kb upstream from J lambda and in the same transcriptional orientation. Eight to twelve variable genes of the same set are found adjacent to the V lambda 1 gene, indicating that V-gene amplification did occur. Three of these genes were sequenced and proved to be pseudogenes, one of them having an inverted polarity. Data suggesting extensive somatic diversification of the V lambda 1 sequence are reported, including the possible use of nonfunctional V elements in a somatic gene-conversion-like process." @default.
• W2014549199 created "2016-06-24" @default.
• W2014549199 creator A5020736484 @default.
• W2014549199 date "1985-02-01" @default.
• W2014549199 modified "2023-10-17" @default.
• W2014549199 title "A single rearrangement event generates most of the chicken immunoglobulin light chain diversity" @default.
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• W2014549199 doi "https://doi.org/10.1016/0092-8674(85)90142-4" @default.
• W2014549199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3917859" @default.
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