Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014557893> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2014557893 endingPage "50" @default.
- W2014557893 startingPage "41" @default.
- W2014557893 abstract "Allergic eye disease has a variety of clinical manifestations including seasonal atopic conjunctivitis (SAC), perennial atopic conjunctivitis (PAC), atopic keratoconjunctivitis (AKC), and atopic blepharoconjunctivitis (ABC). We have investigated the number, distribution and protease expression of mast cells in normal and diseased conjunctiva with the use of immunohistochemistry in water-miscible resin sections. The median mast cell densities in normal subjects were 17 mm-2 in the bulbar substantia propria and 9 mm-2 in tarsal substantia propria. Mast cells were absent from the normal conjunctival epithelium at both sites. Mast cell densities were increased in the bulbar substantia propria in SAC, AKC and ABC. Tarsal substantia propria showed a significant increase in mast cells in ABC and AKC disease states. Mast cells express a range of proteases which varies according to their anatomic site. Mast cells in connective tissue are described to contain tryptase, chymase, cathepsin-G and carboxypeptidase-A, whereas mucosal mast cells contain only tryptase. In the diseased conjunctiva there was a marked reduction in proteases other than tryptase in the intraepithelial mast cells. There were also significant reductions in protease expression other than tryptase in the bulbar substantia propria in AKC and ABC. There appear to be specific alterations in the distribution of mast cells in the sub-categories of allergic eye disease. The distinction between mucosal and connective tissue mast cell phenotypes is not clear-cut and may depend on the functional state of the mast cells in relation to the microenvironment." @default.
- W2014557893 created "2016-06-24" @default.
- W2014557893 creator A5004141628 @default.
- W2014557893 creator A5007874257 @default.
- W2014557893 creator A5013907204 @default.
- W2014557893 creator A5036796028 @default.
- W2014557893 creator A5049984389 @default.
- W2014557893 creator A5089020623 @default.
- W2014557893 date "1995-01-01" @default.
- W2014557893 modified "2023-10-16" @default.
- W2014557893 title "Mast cell distribution and neutral protease expression in acute and chronic allergic conjunctivitis" @default.
- W2014557893 cites W1557019060 @default.
- W2014557893 cites W1967945567 @default.
- W2014557893 cites W1985442986 @default.
- W2014557893 cites W1987403112 @default.
- W2014557893 cites W1990095143 @default.
- W2014557893 cites W1995067489 @default.
- W2014557893 cites W2016801684 @default.
- W2014557893 cites W2041063903 @default.
- W2014557893 cites W2041924938 @default.
- W2014557893 cites W2068970590 @default.
- W2014557893 cites W2072080209 @default.
- W2014557893 cites W2072315546 @default.
- W2014557893 cites W2078646546 @default.
- W2014557893 cites W2080884965 @default.
- W2014557893 cites W2082192343 @default.
- W2014557893 cites W2105122646 @default.
- W2014557893 cites W2160467416 @default.
- W2014557893 cites W2407551786 @default.
- W2014557893 cites W4230056620 @default.
- W2014557893 cites W4298316859 @default.
- W2014557893 doi "https://doi.org/10.1111/j.1365-2222.1995.tb01001.x" @default.
- W2014557893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7728624" @default.
- W2014557893 hasPublicationYear "1995" @default.
- W2014557893 type Work @default.
- W2014557893 sameAs 2014557893 @default.
- W2014557893 citedByCount "52" @default.
- W2014557893 countsByYear W20145578932012 @default.
- W2014557893 countsByYear W20145578932013 @default.
- W2014557893 countsByYear W20145578932014 @default.
- W2014557893 countsByYear W20145578932015 @default.
- W2014557893 countsByYear W20145578932017 @default.
- W2014557893 countsByYear W20145578932018 @default.
- W2014557893 countsByYear W20145578932021 @default.
- W2014557893 countsByYear W20145578932022 @default.
- W2014557893 crossrefType "journal-article" @default.
- W2014557893 hasAuthorship W2014557893A5004141628 @default.
- W2014557893 hasAuthorship W2014557893A5007874257 @default.
- W2014557893 hasAuthorship W2014557893A5013907204 @default.
- W2014557893 hasAuthorship W2014557893A5036796028 @default.
- W2014557893 hasAuthorship W2014557893A5049984389 @default.
- W2014557893 hasAuthorship W2014557893A5089020623 @default.
- W2014557893 hasConcept C142724271 @default.
- W2014557893 hasConcept C181199279 @default.
- W2014557893 hasConcept C182220744 @default.
- W2014557893 hasConcept C203014093 @default.
- W2014557893 hasConcept C2775984611 @default.
- W2014557893 hasConcept C2779726688 @default.
- W2014557893 hasConcept C2780614898 @default.
- W2014557893 hasConcept C2781406822 @default.
- W2014557893 hasConcept C55493867 @default.
- W2014557893 hasConcept C71924100 @default.
- W2014557893 hasConcept C86803240 @default.
- W2014557893 hasConceptScore W2014557893C142724271 @default.
- W2014557893 hasConceptScore W2014557893C181199279 @default.
- W2014557893 hasConceptScore W2014557893C182220744 @default.
- W2014557893 hasConceptScore W2014557893C203014093 @default.
- W2014557893 hasConceptScore W2014557893C2775984611 @default.
- W2014557893 hasConceptScore W2014557893C2779726688 @default.
- W2014557893 hasConceptScore W2014557893C2780614898 @default.
- W2014557893 hasConceptScore W2014557893C2781406822 @default.
- W2014557893 hasConceptScore W2014557893C55493867 @default.
- W2014557893 hasConceptScore W2014557893C71924100 @default.
- W2014557893 hasConceptScore W2014557893C86803240 @default.
- W2014557893 hasIssue "1" @default.
- W2014557893 hasLocation W20145578931 @default.
- W2014557893 hasLocation W20145578932 @default.
- W2014557893 hasOpenAccess W2014557893 @default.
- W2014557893 hasPrimaryLocation W20145578931 @default.
- W2014557893 hasRelatedWork W146106947 @default.
- W2014557893 hasRelatedWork W1571106983 @default.
- W2014557893 hasRelatedWork W1584418244 @default.
- W2014557893 hasRelatedWork W1751541220 @default.
- W2014557893 hasRelatedWork W1751846561 @default.
- W2014557893 hasRelatedWork W2022477746 @default.
- W2014557893 hasRelatedWork W2055379320 @default.
- W2014557893 hasRelatedWork W2068544986 @default.
- W2014557893 hasRelatedWork W2416302103 @default.
- W2014557893 hasRelatedWork W91805268 @default.
- W2014557893 hasVolume "25" @default.
- W2014557893 isParatext "false" @default.
- W2014557893 isRetracted "false" @default.
- W2014557893 magId "2014557893" @default.
- W2014557893 workType "article" @default.