FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014563043> ?p ?o ?g. }

• W2014563043 abstract "To determine the effect of androgens on body composition and muscle strength, we measured fat-free mass (kg), fat mass (kg), and bone density (g/cm2) by dual x-ray absorptiometry, and muscle strength (Newton meters) by dynamometry in a controlled, prospective study involving 13 nonathletic men receiving testosterone enanthate 200 mg/week in for 6 months and 8 healthy controls. Biochemical markers of bone turnover were measured in the treated subjects at baseline and 6 months. In the treated subjects at 6 months, fat-free mass (mean +/- SEM) increased by 9.6 +/- 1.0% (P < or = 0.01) whereas fat mass decreased by 16.2 +/- 6.7% (P < or = 0.05). Changes in muscle strength ranged from -1.6-19.2%. Only hip adduction increased 19.2 +/- 9.5% (P < 0.05). Changes in bone density ranged from -1.3-5.2%, decreasing significantly at one site and increasing significantly at four of the nine sites measured (P < 0.05). Serum testosterone increased by 91.1 +/- 7.5% (P < 0.01), and testicular volume decreased by 24.0 +/- 3.2% (P < 0.01). Serum osteocalcin increased by 35.7 +/- 17.3% (P < 0.05), serum immunoreactive PTH (iPTH) increased by 41.4 +/- 15.1% (P < 0.05), serum calcium decreased by 2.3 +/- 1.0% (P < 0.05), and serum albumin decreased by 4.5 +/- 1.7% (P < 0.05). There were no detectable changes in fat-free mass, fat mass, muscle strength, or bone density in controls. The administration of testosterone enanthate in pharmacological doses for 6 months resulted in a modest reduction in fat mass and small increases in fat-free mass, muscle strength, and bone density. These changes do not support the use of androgens for enhancing athletic performance.In Melbourne, Australia, physicians compared data on 13 healthy, nonathletic, 21-37 year old men receiving an intramuscular injection of 200 mg testosterone enanthate once a week for 6 months with data on 8 age-matched healthy controls to examine the effect of this androgen on body composition and muscle strength and to determine whether it may enhance athletic performance. Dual x-ray absorptiometry measured total body and regional bone density. Dynamometry measured muscle strength. Controls did not experience any detectable changes in fat-free mass, fat mass, muscle strength, or bone density. Between baseline and 6 months of testosterone enanthate treatment, the fat-free mass of cases increased 9.6% (about 6 kg; p .01), while fat mass fell by 16.2% (about 2 kg; p .05). When compared with the literature, however, these changes in body composition were modest. It is not sure whether an increase in lean muscle mass or fluid retention accounted for the increase in fat-free mass. Muscle strength changes varied from -1.6% to 19.2%. Body weight increased by about 5% (around 4 kg). Of the 6 movements, hip adduction was the only significant muscle strength change (increased 19.2%; p .05). Bone density decreased by 1.3% at the skull (p .05), while it increased significantly at the lumbar spine, ribs, pelvis, and femoral neck (p .05). It did not change significantly at the arms, Ward's triangle, trochanter, or legs. The increase in bone density were not enough to reduce the risk of bone fractures. Testosterone enanthate treatment increased serum testosterone levels by 91.1% (p .01), serum osteocalcin by 35.7% (p .05), and the serum immunoreactive parathyrin by 41.4% (p .05). It decreased testicular volume by 24% (p .01), serum calcium levels by 2.3% (p .05), and serum albumin levels by 4.5% (p .05). Based on these findings, androgens, at least in the administered dose range, should not be used to enhance athletic performance." @default.
• W2014563043 created "2016-06-24" @default.
• W2014563043 creator A5014062383 @default.
• W2014563043 creator A5026922332 @default.
• W2014563043 creator A5040485416 @default.
• W2014563043 creator A5055139643 @default.
• W2014563043 date "1993-10-01" @default.
• W2014563043 modified "2023-09-23" @default.
• W2014563043 title "Body composition and muscle strength in healthy men receiving testosterone enanthate for contraception." @default.
• W2014563043 cites W129280754 @default.
• W2014563043 cites W1466567297 @default.
• W2014563043 cites W1794153684 @default.
• W2014563043 cites W1973082936 @default.
• W2014563043 cites W1984304100 @default.
• W2014563043 cites W1987822553 @default.
• W2014563043 cites W1988729531 @default.
• W2014563043 cites W1989061452 @default.
• W2014563043 cites W1997224769 @default.
• W2014563043 cites W2010448321 @default.
• W2014563043 cites W2012178203 @default.
• W2014563043 cites W2020711484 @default.
• W2014563043 cites W2025363664 @default.
• W2014563043 cites W2036287235 @default.
• W2014563043 cites W2052533937 @default.
• W2014563043 cites W2053192941 @default.
• W2014563043 cites W2061152435 @default.
• W2014563043 cites W2071375067 @default.
• W2014563043 cites W2071429181 @default.
• W2014563043 cites W2073209871 @default.
• W2014563043 cites W2074305591 @default.
• W2014563043 cites W2091765881 @default.
• W2014563043 cites W2092699271 @default.
• W2014563043 cites W2096932013 @default.
• W2014563043 cites W2134792323 @default.
• W2014563043 cites W2147956163 @default.
• W2014563043 cites W2150734380 @default.
• W2014563043 cites W2161797688 @default.
• W2014563043 cites W2163585173 @default.
• W2014563043 cites W2256592877 @default.
• W2014563043 cites W2264049293 @default.
• W2014563043 cites W2286058228 @default.
• W2014563043 cites W2335322134 @default.
• W2014563043 cites W2415065152 @default.
• W2014563043 cites W3004702218 @default.
• W2014563043 doi "https://doi.org/10.1210/jcem.77.4.8408450" @default.
• W2014563043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8408450" @default.
• W2014563043 hasPublicationYear "1993" @default.
• W2014563043 type Work @default.
• W2014563043 sameAs 2014563043 @default.
• W2014563043 citedByCount "43" @default.
• W2014563043 countsByYear W20145630432012 @default.
• W2014563043 countsByYear W20145630432013 @default.
• W2014563043 countsByYear W20145630432015 @default.
• W2014563043 countsByYear W20145630432018 @default.
• W2014563043 countsByYear W20145630432019 @default.
• W2014563043 countsByYear W20145630432022 @default.
• W2014563043 crossrefType "journal-article" @default.
• W2014563043 hasAuthorship W2014563043A5014062383 @default.
• W2014563043 hasAuthorship W2014563043A5026922332 @default.
• W2014563043 hasAuthorship W2014563043A5040485416 @default.
• W2014563043 hasAuthorship W2014563043A5055139643 @default.
• W2014563043 hasConcept C126322002 @default.
• W2014563043 hasConcept C131075544 @default.
• W2014563043 hasConcept C134018914 @default.
• W2014563043 hasConcept C160160445 @default.
• W2014563043 hasConcept C181199279 @default.
• W2014563043 hasConcept C185592680 @default.
• W2014563043 hasConcept C2776541429 @default.
• W2014563043 hasConcept C2776886416 @default.
• W2014563043 hasConcept C2779279991 @default.
• W2014563043 hasConcept C2779329777 @default.
• W2014563043 hasConcept C55493867 @default.
• W2014563043 hasConcept C71924100 @default.
• W2014563043 hasConceptScore W2014563043C126322002 @default.
• W2014563043 hasConceptScore W2014563043C131075544 @default.
• W2014563043 hasConceptScore W2014563043C134018914 @default.
• W2014563043 hasConceptScore W2014563043C160160445 @default.
• W2014563043 hasConceptScore W2014563043C181199279 @default.
• W2014563043 hasConceptScore W2014563043C185592680 @default.
• W2014563043 hasConceptScore W2014563043C2776541429 @default.
• W2014563043 hasConceptScore W2014563043C2776886416 @default.
• W2014563043 hasConceptScore W2014563043C2779279991 @default.
• W2014563043 hasConceptScore W2014563043C2779329777 @default.
• W2014563043 hasConceptScore W2014563043C55493867 @default.
• W2014563043 hasConceptScore W2014563043C71924100 @default.
• W2014563043 hasLocation W20145630431 @default.
• W2014563043 hasLocation W20145630432 @default.
• W2014563043 hasOpenAccess W2014563043 @default.
• W2014563043 hasPrimaryLocation W20145630431 @default.
• W2014563043 hasRelatedWork W1964624460 @default.
• W2014563043 hasRelatedWork W2014563043 @default.
• W2014563043 hasRelatedWork W2024215760 @default.
• W2014563043 hasRelatedWork W2054889739 @default.
• W2014563043 hasRelatedWork W2075586630 @default.
• W2014563043 hasRelatedWork W2094162752 @default.
• W2014563043 hasRelatedWork W2108408273 @default.
• W2014563043 hasRelatedWork W2118893132 @default.
• W2014563043 hasRelatedWork W2118931485 @default.
• W2014563043 hasRelatedWork W2119482358 @default.
• W2014563043 isParatext "false" @default.

• next