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- W2014564107 abstract "HereditasVolume 52, Issue 3 p. 271-284 Open Access THE SEQUENCE OF CHROMOSOME ABERRATIONS DURING SV 40 TRANSFORMATION OF A HUMAN DIPLOID CELL STRAIN1 PAUL S. MOORHEAD, PAUL S. MOORHEAD THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA, U.S.A.Search for more papers by this authorEERO SAKSELA, EERO SAKSELA THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA, U.S.A. University Department of Pathology, Maria Hospital, Helsinki.Search for more papers by this author PAUL S. MOORHEAD, PAUL S. MOORHEAD THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA, U.S.A.Search for more papers by this authorEERO SAKSELA, EERO SAKSELA THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA, U.S.A. University Department of Pathology, Maria Hospital, Helsinki.Search for more papers by this author First published: March 1965 https://doi.org/10.1111/j.1601-5223.1965.tb01960.xCitations: 13 1 This work was supported in part by USPHS Career Development Award No. 5-K3-CA-18, 372; USPHS Research Grant No. CA-4534; and Contract No. PH43–62–157 from the National Cancer Institute. § A part of these results was presented at the Symposium on the Characterization and Uses of Human Diploid Strains, Opatija, Yugoslavia, 1963. Proc. edit. Ikic, Institute of Immunology, Zagreb. AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Literature cited Aula, P. 1963. Chromosome breaks in leukocytes of chickenpox patients. Hereditas 49: 451– 453. Bayreuther, K. 1960. Chromosomes in primary neoplastic growth. Nature 186: 6– 9. Chu, E. H. Y., Giles, N. H. and Passano, K. 1961. Types and frequencies of human chromosome aberrations induced by x-rays. Proc. Nat. Acad. Sci. 47: 830– 839. Girardi, A. J., Jensen, F. C. and Koprowski, H. Dynamics of transformation of human tissue culture by SV40. — (In preparation.). Hampar, B. and Ellison, S. A. 1961. Chromosomal aberrations induced by an animal virus. Nature 192: 145– 147. Harnden, D. G. 1964. Cytogenetic studies on patients with virus infections and subjects vaccinated against yellow fever. Amer. J. Hum. Genet. 16: 204– 213. Hayflick, L. and Moorhead, P. S. 1961. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25: 585– 621. Hellström, K. E., Hellström, I. and Sjögren, H. O. 1963. Further studies on karyotypes of a variety of primary and transplanted mouse polyoma tumors. J. Nat. Cancer Inst. 31: 1239– 1253. Jensen, F., Koprowski, H. and Pontén, J. A. 1963. Rapid transformation of human fibroblast cultures by simian virus 40. Proc. Nat. Acad. Sci. 50: 343– 348. Koprowski, H., Pontén, J. A., Jensen, F., Ravdin, R. G., Moorhead, P. and Saksela, E. 1962. Transformation of cultures of human tissue infected with simian virus SV40. J. Cell. and Comp. Physiol. 59: 281– 292. Levan, A. and Biesele, J. J. 1958. The role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells. Ann. N.Y. Acad. Sci. 6: 1022– 1053. Miles, C. P. 1964. Prolonged culture of diploid human cells. Cancer Res. 24: 1070– 1081. Moorhead, P. S. and Saksela, E. 1963. Non-random chromosomal aberrations in SV40-transformed human cells. J. Cell. and Comp. Physiol. 62: 57– 84. Nichols, W. W. 1963. Relationships of viruses, chromosomes and carcinogenesis. Hereditas 50: 53– 80. Nichols, W. W., Levan, A., Hall, B. and Östergren, G. 1962. Measles-associated chromosome breakage. Hereditas 48: 367– 370. Östergren, G. and Wakonig, T. 1954. True or apparent sub-chromatid breakage and the induction of labile states in cytological chromosome loci. Bot. Not. 357– 375. Pontén, J., Jensen, F. and Koprowski, H. 1963. Morphological and virological investigation of human tissue cultures transformed with SV40. J. Cell. and Comp. Physiol. 61: 145– 163. Saksela, E. and Moorhead, P. S. 1962. Enhancement of secondary constrictions and the heterochromatic X in human cells. Cytogenetics 1: 225– 244. Saksela, E. and Moorhead, P. S. 1963. Aneuploidy in the degenerative phase of serial cultivation of human cell strains. Proc. Nat. Acad. Sci. 50: 390– 395. Shein, H. M. and Enders, J. F. 1962. Multiplication and cytopathogenicity of simian vacuolating virus 40 in cultures of human tissues. Proc. Soc. Exp. Biol. Med. 109: 495– 500. Shein, H. M., Enders, J. F., Palmer, L. and Grogan, E. 1964. Further studies on SV40-induced transformation in human renal cell cultures. I. Eventual failure of subcultivation despite a continuing high rate of cell division. Proc. Soc. Exp. Biol. 115: 618– 621. Swim, H. E. and Parker, R. F. 1957. Culture characteristics of human fibroblasts propagated serially. Am. J. Hyg. 66: 235– 243. Todaro, G. J., Wolman, S. R. and Green, H. 1963. Rapid transformation of human fibroblasts with low growth potential into established cell lines by SV40. J. Cell. and Comp. Physiol. 62: 257– 266. Wolman, S. R., Hirschhorn, K. and Todaro, G. J. 1964. Early chromosomal changes in SV40-infected human fibroblast cultures. Cytogenetics 3: 45– 61. Yerganian, G., Shein, H. M. and Enders, J. F. 1962. Chromosomal disturbances observed in human fetal renal cells transformed in vitro by simian virus 40 and carried in culture. Cytogenetics 1: 314– 324. Yoshida, M. C. and Makino, S. 1963. A chromosome study of non-treated and an irradiated human in vitro cell line. Jap. J. Hum. Genet. 5: 39– 45. Citing Literature Volume52, Issue3March 1965Pages 271-284 ReferencesRelatedInformation" @default.
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