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- W2014574557 abstract "Purpose To determine the correlations of pulsatile ocular blood flow (POBF) and intra ocular pressure (IOP) with sleep apnea syndrome (SAS).Methods The study design was cross-sectional. A total number of 26 patients, recruited into the study between January 2006 and February 2008, who underwent polysomnography were selected for the study. All of them were of European Caucasian Origin. The study participants were contacted by telephone and scheduled for eye examination. Sleep apnea syndrome was diagnosed if the apnea-hypopnoea index (AHI) was > 5, based on whole night polysomnographic recordings. Patients with sleep apnea syndrome using CPAP were excluded from the study. Each patient underwent a slit lamp and indirect ophthalmoscope evaluation of anterior and posterior segment as well as pulsatile ocular blood flow (POBF) examination. POBF was recorded in sitting position after instillation of one drop of Alcaine. In this study, only average POBF and IOP were included for the analyses.Results Of them, 17 (65.4%) patients had sleep apnea syndrome (SAS) and 9 (34.6%) patients were healthy and served as the control group. The study revealed that the differences between rates of average POBF and IOP measurements in the SAS group and in the control group were not statistically significant either in the right or in the left eyes (p> 0.05)Conclusion Although, experimental studies showed that POBF was lowered in hypoxia, in our patients there was no correlation between pulsatile ocular blood flow and sleep apnea syndrome. Further investigations, concerning vascular impairment, are needed to give evidence of the mechanism of the optic nerve damage in the SAS." @default.
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- W2014574557 date "2008-09-04" @default.
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- W2014574557 title "The pulsatile ocular blood flow (POBF) in patients with sleep apnea syndrome (SAS)" @default.
- W2014574557 doi "https://doi.org/10.1111/j.1755-3768.2008.6347.x" @default.
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