FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014594787> ?p ?o ?g. }

• W2014594787 endingPage "486" @default.
• W2014594787 startingPage "478" @default.
• W2014594787 abstract "In this work, brain cell metabolism was investigated by 13C NMR spectroscopy and metabolic flux analysis (MFA). Monotypic cultures of astrocytes were incubated with labeled glucose for 38 h, and the distribution of the label was analyzed by 13C NMR spectroscopy. The analysis of the spectra reveals two distinct physiological states characterized by different ratios of pyruvate carboxylase to pyruvate dehydrogenase activities (PC/PDH). Intracellular flux distributions for both metabolic states were estimated by MFA using the isotopic information and extracellular rate measurements as constraints. The model was subsequently checked with the consistency index method. From a biological point of view, the occurrence of the two physiological states appears to be correlated with the presence or absence of extracellular glutamate. Concerning the model, it can be stated that the metabolic network and the set of constraints adopted provide a consistent and robust characterization of the astrocytic metabolism, allowing for the calculation of central intracellular fluxes such as pyruvate recycling, the anaplerotic flux mediated by pyruvate carboxylase, and the glutamine formation through glutamine synthetase." @default.
• W2014594787 created "2016-06-24" @default.
• W2014594787 creator A5003864155 @default.
• W2014594787 creator A5034295628 @default.
• W2014594787 creator A5041231390 @default.
• W2014594787 creator A5059860426 @default.
• W2014594787 creator A5074787856 @default.
• W2014594787 date "2008-02-01" @default.
• W2014594787 modified "2023-10-03" @default.
• W2014594787 title "Combining metabolic flux analysis tools and 13C NMR to estimate intracellular fluxes of cultured astrocytes" @default.
• W2014594787 cites W111736103 @default.
• W2014594787 cites W1522786769 @default.
• W2014594787 cites W1806555373 @default.
• W2014594787 cites W1888519824 @default.
• W2014594787 cites W1976400860 @default.
• W2014594787 cites W1983848089 @default.
• W2014594787 cites W1986130675 @default.
• W2014594787 cites W1986860566 @default.
• W2014594787 cites W1995977817 @default.
• W2014594787 cites W1996622604 @default.
• W2014594787 cites W2000367085 @default.
• W2014594787 cites W2012998132 @default.
• W2014594787 cites W2015150598 @default.
• W2014594787 cites W2015747402 @default.
• W2014594787 cites W2022188529 @default.
• W2014594787 cites W2026161384 @default.
• W2014594787 cites W2039711331 @default.
• W2014594787 cites W2042997049 @default.
• W2014594787 cites W2071145047 @default.
• W2014594787 cites W2073155069 @default.
• W2014594787 cites W2083942245 @default.
• W2014594787 cites W2084423194 @default.
• W2014594787 cites W2086914035 @default.
• W2014594787 cites W2092635505 @default.
• W2014594787 cites W2094936373 @default.
• W2014594787 cites W2107792766 @default.
• W2014594787 cites W2111102591 @default.
• W2014594787 cites W2128005489 @default.
• W2014594787 cites W2130568001 @default.
• W2014594787 cites W2133783666 @default.
• W2014594787 cites W2163855763 @default.
• W2014594787 cites W2169826322 @default.
• W2014594787 cites W4233604467 @default.
• W2014594787 cites W4245160204 @default.
• W2014594787 doi "https://doi.org/10.1016/j.neuint.2007.08.007" @default.
• W2014594787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17904693" @default.
• W2014594787 hasPublicationYear "2008" @default.
• W2014594787 type Work @default.
• W2014594787 sameAs 2014594787 @default.
• W2014594787 citedByCount "29" @default.
• W2014594787 countsByYear W20145947872012 @default.
• W2014594787 countsByYear W20145947872013 @default.
• W2014594787 countsByYear W20145947872014 @default.
• W2014594787 countsByYear W20145947872016 @default.
• W2014594787 countsByYear W20145947872017 @default.
• W2014594787 countsByYear W20145947872018 @default.
• W2014594787 countsByYear W20145947872019 @default.
• W2014594787 crossrefType "journal-article" @default.
• W2014594787 hasAuthorship W2014594787A5003864155 @default.
• W2014594787 hasAuthorship W2014594787A5034295628 @default.
• W2014594787 hasAuthorship W2014594787A5041231390 @default.
• W2014594787 hasAuthorship W2014594787A5059860426 @default.
• W2014594787 hasAuthorship W2014594787A5074787856 @default.
• W2014594787 hasConcept C101810790 @default.
• W2014594787 hasConcept C12554922 @default.
• W2014594787 hasConcept C140137476 @default.
• W2014594787 hasConcept C160941953 @default.
• W2014594787 hasConcept C178790620 @default.
• W2014594787 hasConcept C181199279 @default.
• W2014594787 hasConcept C185592680 @default.
• W2014594787 hasConcept C2779349466 @default.
• W2014594787 hasConcept C28406088 @default.
• W2014594787 hasConcept C515207424 @default.
• W2014594787 hasConcept C55493867 @default.
• W2014594787 hasConcept C62231903 @default.
• W2014594787 hasConcept C66974803 @default.
• W2014594787 hasConcept C68709404 @default.
• W2014594787 hasConcept C71240020 @default.
• W2014594787 hasConcept C79879829 @default.
• W2014594787 hasConcept C86803240 @default.
• W2014594787 hasConcept C88099638 @default.
• W2014594787 hasConceptScore W2014594787C101810790 @default.
• W2014594787 hasConceptScore W2014594787C12554922 @default.
• W2014594787 hasConceptScore W2014594787C140137476 @default.
• W2014594787 hasConceptScore W2014594787C160941953 @default.
• W2014594787 hasConceptScore W2014594787C178790620 @default.
• W2014594787 hasConceptScore W2014594787C181199279 @default.
• W2014594787 hasConceptScore W2014594787C185592680 @default.
• W2014594787 hasConceptScore W2014594787C2779349466 @default.
• W2014594787 hasConceptScore W2014594787C28406088 @default.
• W2014594787 hasConceptScore W2014594787C515207424 @default.
• W2014594787 hasConceptScore W2014594787C55493867 @default.
• W2014594787 hasConceptScore W2014594787C62231903 @default.
• W2014594787 hasConceptScore W2014594787C66974803 @default.
• W2014594787 hasConceptScore W2014594787C68709404 @default.
• W2014594787 hasConceptScore W2014594787C71240020 @default.
• W2014594787 hasConceptScore W2014594787C79879829 @default.
• W2014594787 hasConceptScore W2014594787C86803240 @default.

• next