FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2014604915> ?p ?o ?g. }

• W2014604915 endingPage "414" @default.
• W2014604915 startingPage "412" @default.
• W2014604915 abstract "Deltamethrin (DLM), [(S)-α-cyano-d-phenoxybenzyl-(1R,3R)-e-(2,2 dibromovinyl)-2,2-dimethylcyclo-propane-1-carboxylate], is a pyrethroid insecticide widely used in agriculture and households. There are several methods for analysis of DLM in biological fluids and tissues, but these methods are time consuming. They generally involve the extraction of DLM with lipid-soluble solvents such as n-pentane, n-hexane, diethylether or acetone, and subsequent evaporation of the solvent. A more rapid and sensitive high-performance liquid chromatography (HPLC) method to analyze DLM in plasma and tissues (liver, kidney, and brain) was developed and validated according to U.S. Food and Drug Administration (U.S. FDA) and International Conference on Harmonization (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use guidelines. The limit of detection (S/N of 3/1) for DLM was 0.01 μg/ml for plasma, liver, kidney and brain. The method performances were shown to be selective for DLM and linear over the concentration range 0.01–20.0 μg/ml. For five replications of samples at 0.05, 0.1, 0.2, 1.5 and 4.0 μg/ml, intraday precision and accuracy values were in the range of 0.7–13.1% relative standard deviation (%R.S.D.) and 1.8–14.1%Error, respectively. Interday (n = 15) precision and accuracy values at 0.05, 0.1, 0.2, 1.5, and 4.0 μg/ml were in the range of 3.2–15.2% (%R.S.D.) and 3.7–14.8%Error, respectively. The absolute recoveries of DLM ranged from 93 to 103% for plasma, 95 to 114% for liver, 97 to 108% for kidney, and 95 to 108% for brain. This method can be quite useful for DLM pharmacokinetic and tissue distribution studies, for which multiple plasma and tissue samples have to be analyzed quickly with high reproducibility." @default.
• W2014604915 created "2016-06-24" @default.
• W2014604915 creator A5014979991 @default.
• W2014604915 creator A5057513702 @default.
• W2014604915 creator A5058668048 @default.
• W2014604915 creator A5079742026 @default.
• W2014604915 date "1979-05-01" @default.
• W2014604915 modified "2023-09-26" @default.
• W2014604915 title "High-performance liquid chromatography of decamethrim" @default.
• W2014604915 cites W1970319073 @default.
• W2014604915 cites W2023793137 @default.
• W2014604915 cites W2042328076 @default.
• W2014604915 cites W2044095974 @default.
• W2014604915 doi "https://doi.org/10.1016/s0021-9673(00)92313-6" @default.
• W2014604915 hasPublicationYear "1979" @default.
• W2014604915 type Work @default.
• W2014604915 sameAs 2014604915 @default.
• W2014604915 citedByCount "21" @default.
• W2014604915 crossrefType "journal-article" @default.
• W2014604915 hasAuthorship W2014604915A5014979991 @default.
• W2014604915 hasAuthorship W2014604915A5057513702 @default.
• W2014604915 hasAuthorship W2014604915A5058668048 @default.
• W2014604915 hasAuthorship W2014604915A5079742026 @default.
• W2014604915 hasConcept C119128265 @default.
• W2014604915 hasConcept C178790620 @default.
• W2014604915 hasConcept C179998833 @default.
• W2014604915 hasConcept C185592680 @default.
• W2014604915 hasConcept C2777077568 @default.
• W2014604915 hasConcept C2777589835 @default.
• W2014604915 hasConcept C2780471494 @default.
• W2014604915 hasConcept C2781213060 @default.
• W2014604915 hasConcept C43617362 @default.
• W2014604915 hasConceptScore W2014604915C119128265 @default.
• W2014604915 hasConceptScore W2014604915C178790620 @default.
• W2014604915 hasConceptScore W2014604915C179998833 @default.
• W2014604915 hasConceptScore W2014604915C185592680 @default.
• W2014604915 hasConceptScore W2014604915C2777077568 @default.
• W2014604915 hasConceptScore W2014604915C2777589835 @default.
• W2014604915 hasConceptScore W2014604915C2780471494 @default.
• W2014604915 hasConceptScore W2014604915C2781213060 @default.
• W2014604915 hasConceptScore W2014604915C43617362 @default.
• W2014604915 hasIssue "2" @default.
• W2014604915 hasLocation W20146049151 @default.
• W2014604915 hasOpenAccess W2014604915 @default.
• W2014604915 hasPrimaryLocation W20146049151 @default.
• W2014604915 hasRelatedWork W1964259887 @default.
• W2014604915 hasRelatedWork W1998279148 @default.
• W2014604915 hasRelatedWork W2013299392 @default.
• W2014604915 hasRelatedWork W2032191029 @default.
• W2014604915 hasRelatedWork W2069812479 @default.
• W2014604915 hasRelatedWork W2084062459 @default.
• W2014604915 hasRelatedWork W2155596957 @default.
• W2014604915 hasRelatedWork W2392582009 @default.
• W2014604915 hasRelatedWork W2411946260 @default.
• W2014604915 hasRelatedWork W3152281345 @default.
• W2014604915 hasVolume "173" @default.
• W2014604915 isParatext "false" @default.
• W2014604915 isRetracted "false" @default.
• W2014604915 magId "2014604915" @default.
• W2014604915 workType "article" @default.